Pharmacogenetics of carbamazepine and valproate: focus on polymorphisms of drug metabolizing enzymes and transporters

T Iannaccone, C Sellitto, V Manzo, F Colucci… - Pharmaceuticals, 2021 - mdpi.com
Pharmacogenomics can identify polymorphisms in genes involved in drug pharmacokinetics
and pharmacodynamics determining differences in efficacy and safety and causing inter …

Pharmacogenetics in primary headache disorders

II Belyaeva, AG Subbotina, II Eremenko… - Frontiers in …, 2022 - frontiersin.org
Primary headache disorders, such as migraine, tension-type headache (TTH), and cluster
headache, belong to the most common neurological disorders affecting a high percentage of …

In Silico Tools to Thaw the Complexity of the Data: Revolutionizing Drug Research in Drug Metabolism, Pharmacokinetics and Toxicity Prediction

H Sree Kommalapati, P Pilli, VM Golla… - Current Drug …, 2023 - benthamdirect.com
In silico tool is the flourishing pathway for Researchers and budding chemists to strain the
analytical data in a snapshot. Traditionally, drug research has heavily relied on labor …

The effect of cannabidiol on the pharmacokinetics of carbamazepine in rats

RS Darweesh, TN Khamis, T El-Elimat - Naunyn-Schmiedeberg's Archives …, 2020 - Springer
Carbamazepine (CBZ) is mainly metabolized by CYP3A4 into carbamazepine-10, 11-
epoxide (CBZE). Cannabidiol (CBD) is a potent inhibitor of the CYP3A family. The aim of this …

Pharmacogenetics of Carbamazepine: A Systematic Review on CYP3A4 and CYP3A5 Polymorphisms

R Riffi, W Boughrara, A Chentouf, W Ilias… - CNS & Neurological …, 2024 - benthamdirect.com
Background and Objective The association between carbamazepine (CBZ) metabolism and
resistance in epilepsy and the genetic polymorphisms of CYP3A5 (rs776746 and rs15524) …

[PDF][PDF] Особенности фармакогенетики карбамазепина и наиболее частые нежелательные лекарственные реакции на фоне его применения (обзор …

ВЮ Скрябин, МС Застрожин, ЕА Брюн… - Обзоры по …, 2022 - researchgate.net
В обзоре систематизирована и представлена актуальная информация, касающаяся
фармакокинетики и фармакогенетики карбамазепина, а также наиболее …

Pooled bioequivalence study database from Turkey: characterization of adverse events and determination of split points based on Gini Index as a promising method

Ç Gurer, A Çakmak Pehlivanli, G Çakmak Demircigil - Springerplus, 2016 - Springer
Background Manufacturing of and medication with generic drugs is increasing around the
world. Bioequivalence (BE) studies are being performed routinely by Contract Research …

Peculiarities of carbamazepine pharmacogenetics and the most common adverse drug reactions during its use (literature review)

VY Skryabin, MS Zastrozhin… - Reviews on Clinical …, 2022 - journals.eco-vector.com
Особенности фармакогенетики карбамазепина и наиболее частые нежелат Page 1 255
Лицензия CC BY-NC-ND 4.0 © Коллектив авторов, 2022 Обзоры по клинической …

Carbamazepine Resistance in Epileptic Patients & Its Association with Genetic Polymorphism

J Mubarak, HH Bangash, ZB Manzoor… - Precision Medicine …, 2023 - rootspress.org
Epilepsy is a brain disorder with a lasting tendency to produce epileptic episodes. It carries
neurological, cognitive, psychological, and social consequences. Carbamazepine (CBZ) is …

Therapeutic Monitoring of Carbamazepine in Individuals with Neurodevelopmental Disorders Using LC-MS/MS in Relationship with CYP and SULT Genes

SF Khallad - 2021 - search.proquest.com
Background| Individuals diagnosed with neurodevelopmental disorders like Autism
Spectrum Disorder (ASD) and intellectual disability (ID) are administered pharmacological …