The 2018 marine pharmacology literature review represents a continuation of the previous
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …

The present global COVID-19 pandemic caused by the noble pleomorphic severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a vulnerable situation in the …

Background Actinomycetes associated with marine sponge represent a promising source of
bioactive compounds. Herein, we report the isolation, identification, and bioactivity …

Humans have been suffered from viral infections over the centuries, such as influenza, HSV,
and HIV, which have killed millions of people worldwide. However, the availability of …

Huperzine A (HupA) is a plant-derived lycopodium alkaloid used for the treatment of
Alzheimer's disease due to its inhibition against acetylcholinesterase. Currently, industrial …

Viruses have always been a class of pathogenic microorganisms that threaten the health
and safety of human life worldwide. However, for a long time, the treatment of viral infections …

Novel anti-viral natural product ε-poly-l-lysine (ε-PL) produced by Streptomyces is a
homopolymer of l-lysine, of which the underlying molecular mode of action remains to be …

Worldwide urbanization and subsequent migration have accelerated the emergence and
spread of diverse novel human diseases. Among them, diseases caused by viruses could …

Microbial natural products and their derivatives have been developed as a considerable part
of clinical drugs and agricultural chemicals. Marine microbial natural products exhibit …

Actinomycetes are an incredibly prolific source of therapeutic secondary metabolites.
Indeed, over 50% of currently used commercial antibiotics are of actinomycetal origin …