Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

Frailty can be viewed as a state of physiological decline that increases susceptibility to
adverse health outcomes. This loss of physiological reserve means that even small stressors …

Background Elevated blood pressure and elevated low-density lipoprotein (LDL) cholesterol
increase the risk of cardiovascular disease. Lowering both should reduce the risk of …

Aims Physical frailty is a commonly encountered geriatric syndrome among older adults
without coronary heart disease (CHD). The impact of frailty on the incidence of long-term …

Abstract Purpose of Review Biological age is the concept of using biophysiological
measures to more accurately determine an individual's age-related risk of adverse …

Objective To optimise dementia prevention strategies, we must understand the complex
relationships between lifestyle behaviours, frailty and genetics. Methods We explored …

As the population ages, the global cardiovascular disease burden will continue to increase,
particularly among older adults. Increases in life expectancy and better cardiovascular care …

At least half of all patients with heart failure (HF) are affected by frailty, a syndrome that limits
an individual ability to recover from acute stressors. While frailty affects up to 90% of patients …

Aims Frailty is associated with an increased risk of all-cause mortality and cardiovascular
(CV) events. Limited data exist from the modern era of CV prevention on the relationship …

Background and Purpose: Conditions associated with frailty are common in people
experiencing stroke and may explain differences in outcomes. We assessed associations …