Pulmonary functional imaging: Part 1—state-of-the-art technical and physiologic underpinnings

Y Ohno, JB Seo, G Parraga, KS Lee, WB Gefter… - Radiology, 2021 - pubs.rsna.org
Over the past few decades, pulmonary imaging technologies have advanced from chest
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …

19F MRI of the Lungs Using Inert Fluorinated Gases: Challenges and New Developments

MJ Couch, IK Ball, T Li, MS Fox… - Journal of Magnetic …, 2019 - Wiley Online Library
Fluorine‐19 (19F) MRI using inhaled inert fluorinated gases is an emerging technique that
can provide functional images of the lungs. Inert fluorinated gases are nontoxic, abundant …

3D phase‐resolved functional lung ventilation MR imaging in healthy volunteers and patients with chronic pulmonary disease

F Klimeš, A Voskrebenzev, M Gutberlet… - Magnetic …, 2021 - Wiley Online Library
Purpose To test the feasibility of 3D phase‐resolved functional lung (PREFUL) MRI in
healthy volunteers and patients with chronic pulmonary disease, to compare 3D to 2D …

Comparison of functional free-breathing pulmonary 1H and hyperpolarized 129Xe magnetic resonance imaging in pediatric cystic fibrosis

MJ Couch, S Munidasa, JH Rayment… - Academic radiology, 2021 - Elsevier
Rationale and Objectives Phase resolved functional lung (PREFUL) magnetic resonance
imaging (MRI) is a free-breathing 1 H-based technique that produces maps of fractional …

Flow Volume Loop and Regional Ventilation Assessment Using Phase‐Resolved Functional Lung (PREFUL) MRI: Comparison With 129Xenon Ventilation MRI and …

TF Kaireit, A Kern, A Voskrebenzev… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Regional flow volume loop ventilation‐weighted noncontrast‐enhanced proton
lung MRI in free breathing has emerged as a novel technique for assessment of regional …

Quantification of pulmonary perfusion abnormalities using DCE-MRI in COPD: comparison with quantitative CT and pulmonary function

M Schiwek, SMF Triphan, J Biederer, O Weinheimer… - European …, 2022 - Springer
Objectives Pulmonary perfusion abnormalities are prevalent in patients with chronic
obstructive pulmonary disease (COPD), are potentially reversible, and may be associated …

Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Free‐breathing quantification of regional ventilation derived by phase‐resolved functional lung (PREFUL) MRI

F Klimeš, A Voskrebenzev, M Gutberlet… - NMR in …, 2019 - Wiley Online Library
Purpose To test the feasibility of regional fully quantitative ventilation measurement in free
breathing derived by phase‐resolved functional lung (PREFUL) MRI in the supine and …

Pulmonary ventilation maps generated with free-breathing proton MRI and a deep convolutional neural network

DPI Capaldi, F Guo, L Xing, G Parraga - Radiology, 2021 - pubs.rsna.org
Background Hyperpolarized noble gas MRI helps measure lung ventilation, but clinical
translation remains limited. Free-breathing proton MRI may help quantify lung function using …

Specific Ventilation in Severe Asthma Evaluated with Noncontrast Tidal Breathing 1H MRI

DPI Capaldi, NB Konyer, M Kjarsgaard… - Radiology …, 2023 - pubs.rsna.org
Purpose To determine if proton (1H) MRI–derived specific ventilation is responsive to
bronchodilator (BD) therapy and associated with clinical biomarkers of type 2 airway …