Cancer-associated fibroblasts: Origin, function, imaging, and therapeutic targeting
The tumor microenvironment (TME) is emerging as one of the primary barriers in cancer
therapy. Cancer-associated fibroblasts (CAF) are a common inhabitant of the TME in several …
therapy. Cancer-associated fibroblasts (CAF) are a common inhabitant of the TME in several …
Engineered nanomedicines with enhanced tumor penetration
Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …
Triple-negative breast cancer: a review of conventional and advanced therapeutic strategies
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …
Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: A combinational approach for enhanced delivery of nanoparticles
Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …
Gold-nanoparticle-assisted plasmonic photothermal therapy advances toward clinical application
MRK Ali, Y Wu, MA El-Sayed - The Journal of Physical Chemistry …, 2019 - ACS Publications
Plasmonic photothermal therapy (PPTT), a type of treatment involving the intravenous or
intratumoral injection to introduce gold nanoparticles to cancerous cells and the subsequent …
intratumoral injection to introduce gold nanoparticles to cancerous cells and the subsequent …
Diverse applications of nanomedicine
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …
health-related issues continues to receive increasing interest. Research in nanomedicine …
Synthesis, bioactive properties, and biomedical applications of intrinsically therapeutic nanoparticles for disease treatment
DD Nguyen, JY Lai - Chemical Engineering Journal, 2022 - Elsevier
Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …
capabilities of self-triggering bioactive activities (without drug) when interacting with …
Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy
Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …
against cancers. Despite these advancements, challenges remain, particularly in the clinical …
Recent advances in nanoparticles mediated photothermal therapy induced tumor regression
Photothermal therapy (PTT) is a minimally invasive procedure for treating cancer. The two
significant prerequisites of PTT are the photothermal therapeutic agent (PTA) and near …
significant prerequisites of PTT are the photothermal therapeutic agent (PTA) and near …
Nanoparticle-mediated remodeling of the tumor microenvironment to enhance immunotherapy
Nanoscience has long been lauded as a method through which tumor-associated barriers
could be overcome. As successful as cancer immunotherapy has been, limitations …
could be overcome. As successful as cancer immunotherapy has been, limitations …