Antibiotic resistance is a global public health threat. The care of chronic infections is
complicated by bacterial biofilms. Biofilm embedded cells can be up to 1000-fold more …

RirA is a global iron regulator in diverse Alphaproteobacteria that belongs to the Rrf2
superfamily of transcriptional regulators, which can contain an iron–sulfur (Fe–S) cluster …

Molybdenum cofactor (Moco) biosynthesis is a complex process that involves the
coordinated function of several proteins. In the recent years it has become evident that the …

The role of the iron–sulfur [Fe-S] cluster transcriptional regulator IscR in maintaining [Fe-S]
homeostasis in bacteria is still poorly characterized in many groups. Caulobacter crescentus …

Iron (Fe) is a trace nutrient required by nearly all organisms. As a result of the demand for Fe
and the toxicity of non-chelated cytosolic ionic Fe, regulatory systems have evolved to tightly …

Engineering microbial cells for the commercial production of biomolecules and biochemicals
requires understanding how cells respond to dynamically changing substrate (feast–famine) …

Pathogenic bacteria employ complex systems to cope with metal ion shortage conditions
and propagate in the host. IsrR is a regulatory RNA (sRNA) whose activity is decisive for …

Escherichia coli ferric uptake regulator (Fur) binds a [2Fe–2S] cluster, not a mononuclear
iron, when the intracellular free iron content is elevated in E. coli cells. Here we report that …

Abstract Cyclo (Phe-Pro)(cFP), a cyclic dipeptide with notable antifungal, antibacterial, and
antiviral properties, shows great promise for biological control of plant diseases. Produced …

It was generally postulated that when intracellular free iron content is elevated in bacteria,
the ferric uptake regulator (Fur) binds its corepressor a mononuclear ferrous iron to regulate …