Cisplatin is one of the most effective chemotherapy drugs for ovarian cancer, but resistance
is common. The initial response to platinum‑based chemotherapy is as high as 80%, but in …

Curative cancer therapy remains a major challenge particularly in cancers displaying
multidrug resistance (MDR). The MDR phenotype is characterized by cross-resistance to a …

Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …

Background Chemotherapy resistance is a primary reason of ovarian cancer therapy failure;
hence it is important to investigate the underlying mechanisms of chemotherapy resistance …

We are experiencing a revolution in cancer. Advances in screening, targeted and immune
therapies, big data, computational methodologies, and significant new knowledge of cancer …

Ivermectin is a macrolide antiparasitic drug with a 16-membered ring that is widely used for
the treatment of many parasitic diseases such as river blindness, elephantiasis and scabies …

Background: Ovarian cancer (OC), a serious gynecological malignant disease, remains an
enormous challenge in early diagnosis and medical treatment. Based on the GEO and …

In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene
RAD51C are established drivers of defective homologous recombination and are emerging …

The intraperitoneal administration of chemotherapeutics has emerged as a potential route in
ovarian cancer treatment. Nanoparticles as carriers for these agents could be interesting by …

Simple Summary In the precision medicine era, epithelial ovarian cancer (EOC) is
characterized by a high death-to-incidence rate and poor 5-year survival. The identification …