Regeneration of fat cells from myofibroblasts during wound healing

MV Plikus, CF Guerrero-Juarez, M Ito, YR Li… - Science, 2017 - science.org
Although regeneration through the reprogramming of one cell lineage to another occurs in
fish and amphibians, it has not been observed in mammals. We discovered in the mouse …

Functions of the SNAI family in chondrocyte‐to‐osteocyte development

E Razmara, A Bitaraf, B Karimi… - Annals of the New York …, 2021 - Wiley Online Library
Different cellular mechanisms contribute to osteocyte development. And while critical roles
for members of the zinc finger protein SNAI family (SNAIs) have been discussed in cancer …

[HTML][HTML] New insights into the diverse functions of the NR2F nuclear orphan receptor family

T Sajinovic, G Baier - Frontiers in Bioscience-Landmark, 2023 - imrpress.com
Following gene expansion during evolution, today's phylogenetic tree of the NR2F family of
nuclear orphan receptors in mammals is represented by three different isoforms: NR2F1 …

In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer …

A Montero-Calle, Á López-Janeiro, ML Mendes… - Cellular Oncology, 2023 - Springer
Background Endometrial cancer (EC) is the most common cancer of the female reproductive
organs. Despite the good overall prognosis of most low-grade ECs, FIGO I and FIGO II …

Regulation of orbital fibrosis and adipogenesis by pathogenic Th17 cells in Graves orbitopathy

S Fang, Y Huang, S Zhong, Y Li, Y Zhang… - The Journal of …, 2017 - academic.oup.com
Context T helper (Th) 17 cells are correlated with many human autoimmune disorders,
including Graves disease, and may play key roles in the pathogenesis of Graves orbitopathy …

Metabolic reprogramming helps to define different metastatic tropisms in colorectal cancer

A Montero-Calle, M Gómez de Cedrón… - Frontiers in …, 2022 - frontiersin.org
Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases,
with the most frequent target organs being the liver and lung. Metabolic reprogramming has …

Proteomics analysis of prefrontal cortex of Alzheimer's disease patients revealed dysregulated proteins in the disease and novel proteins associated with amyloid-β …

A Montero-Calle, R Coronel… - Cellular and Molecular …, 2023 - Springer
Background Alzheimer's disease (AD) is a progressive, chronic, and neurodegenerative
disease, and the most common cause of dementia worldwide. Currently, the mechanisms …

Graphene quantum dots-functionalized multi-walled carbon nanotubes as nanocarriers in electrochemical immunosensing. Determination of IL-13 receptor α2 in …

V Serafín, A Valverde, G Martínez-García… - Sensors and Actuators B …, 2019 - Elsevier
In this work, the development of the first integrated electrochemical immunosensor for the
determination of the IL-13Rα2 is reported. The strategy involves the immobilization of a …

Proteomics and transcriptome reveal the key transcription factors mediating the protection of Panax notoginseng saponins (PNS) against cerebral ischemia …

J Zhang, F Guo, R Zhou, C Xiang, Y Zhang, J Gao… - Phytomedicine, 2021 - Elsevier
Background and purpose Transcription factors (TFs) play a critical role in the cerebral
ischemia/reperfusion injury (IRI). Panax notoginseng saponins (PNS) are extensively used …

Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis

M Garranzo-Asensio, P San Segundo-Acosta… - Journal of …, 2020 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer related death worldwide. Its diagnosis at early stages would significantly improve the …