New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia

E Voskaridou, E Terpos - British Journal of Haematology, 2004 - Wiley Online Library
Osteoporosis represents an important cause of morbidity in adult patients with thalassaemia
major (TM). The pathogenesis of osteoporosis in TM is multifactorial, and includes bone …

Bone disease and skeletal complications in patients with β thalassemia major

R Haidar, KM Musallam, AT Taher - Bone, 2011 - Elsevier
Increased survival in patients with β thalassemia major (TM) allowed for several
complications of the disease and its treatment to manifest, one of which is bone disease …

Bone disease in thalassemia: a molecular and clinical overview

P Wong, PJ Fuller, MT Gillespie, F Milat - Endocrine reviews, 2016 - academic.oup.com
Thalassemia bone disease is a common and severe complication of thalassemia—an
inherited blood disorder due to mutations in the α or β hemoglobin gene. In its more severe …

Evaluation of osseous changes in dental panoramic radiography of thalassemia patients using mandibular indexes and fractal size analysis

S Bayrak, D Göller Bulut, K Orhan, EA Sinanoğlu… - Oral radiology, 2020 - Springer
Objective This study aimed to evaluate the radiomorphometric indexes and fractal
dimension (FD) on dental panoramic radiography (DPR) of Thalassemia Major (TM) …

New strategies in the treatment of the thalassemias

SL Schrier, E Angelucci - Annu. Rev. Med., 2005 - annualreviews.org
In addition to the severe beta thalassemias, hematologists have begun to recognize the
more severe forms of alpha thalassemia, namely hemoglobin (Hb) H disease and Hb H/Hb …

Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD Pediatric Official Positions

N Bishop, P Braillon, J Burnham, R Cimaz… - Journal of clinical …, 2008 - Elsevier
The Task Force focusing on the use of dual energy X-ray absorptiometry (DXA) in children
and adolescents with diseases that may affect the skeleton reviewed over 300 articles to …

Bone disease in β thalassemia patients: past, present and future perspectives

V De Sanctis, AT Soliman, H Elsefdy, N Soliman… - Metabolism, 2018 - Elsevier
Bone disorders in patients with thalassemia major (TM) and intermedia (TI) constitute
complex conditions that result from various factors affecting the growing skeleton. Although …

Thalassemia-associated osteoporosis: a systematic review on treatment and brief overview of the disease

AD Dede, G Trovas, E Chronopoulos… - Osteoporosis …, 2016 - Springer
Thalassemia-associated osteoporosis constitutes a major complication in patients with
thalassemia. This review presents the existing studies on the treatment of thalassemia …

Pamidronate is an effective treatment for osteoporosis in patients with beta‐thalassaemia

E Voskaridou, E Terpos, G Spina… - British Journal of …, 2003 - Wiley Online Library
Osteoporosis in beta‐thalassaemia is multifactorial; increased osteoclast function seems to
play an important role in its pathogenesis. The aim of this study was to evaluate the effect of …

Treatment options for thalassemia patients with osteoporosis

E Terpos, E Voskaridou - Annals of the New York Academy of …, 2010 - Wiley Online Library
Osteoporosis represents a prominent cause of morbidity in patients with thalassemia. The
delay in sexual maturation, the presence of diabetes and hypothyroidism, the parathyroid …