Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …

Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …

Introduction Inflammation is a defensive response of the organism to irritation which is
manifested by redness, swelling, heat, pain and dysfunction. The inflammatory response …

Cisplatin is widely recommended in combination for the treatment of tumors, thus inevitably
increasing the incidence of cisplatin-induced acute kidney injury. Mitophagy is a type of …

The side effects of cisplatin, a widely used chemotherapeutic agent, include nephrotoxicity.
Previous studies have reported that cisplatin induces ferroptosis and lipid peroxide …

An important pathophysiological process of acute kidney injury (AKI) is mitochondrial
fragmentation in renal tubular epithelial cells, which leads to cell death. Pyruvate kinase M2 …

Acute kidney injury (AKI), a common and serious clinical kidney syndrome with high
incidence and mortality, is caused by multiple pathogenic factors, such as ischemia …

Global obesity epidemics impacts human health and causes obesity-related illnesses,
including the obesity-related kidney and liver diseases. UTX, a histone H3K27 demethylase …

Emerging evidence suggests that ferroptosis is highly correlated with the pathogenesis of
acute kidney injury (AKI). Ferroptosis, an iron‐dependent form of cell death, is manifested by …

Acute kidney injury (AKI), one of the most prevalent clinical diseases with a high incidence
rate worldwide, is characterized by a rapid deterioration of renal function and further triggers …