Preconception and prenatal exposure to environmental contaminants may affect future
health. Pregnancy and early life are critical sensitive windows of susceptibility. The aim of …

Fetal growth is regulated by a complex interaction of maternal, placental, and fetal factors.
The effects and outcomes that chemicals, widely distributed in the environment, may have …

A variety of experimental and epidemiological studies lend support to the Developmental
Origin of Health and Disease (DOHaD) concept. Yet, the actual mechanisms accounting for …

Increasing evidence has associated the exposure of endocrine-disrupting chemicals (EDCs)
with the cardiovascular (CV) system. This exposure is particularly problematic in a sensitive …

Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …

The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …

Environmental chemicals comprise a major portion of the human exposome, with some
shown to impact the health of susceptible populations, including pregnant women and …

Emerging pollutants represent a group of synthetic or naturally occurring compounds that
are not normally monitored within the environment but can enter into the environment and …

Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar
cells examined individually has prompted interest in obtaining parallel methylome data. We …

DNA methylation occurs primarily at cytosine in cytosine-guanine dinucleotides (CpG) and
involves the addition of a methyl group to carbon number 5 in cytosine to form 5 …