A review of recent advances in the modeling of nanoparticle radiosensitization with the Geant4-DNA toolkit

A Taheri, MU Khandaker, F Moradi… - Radiation Physics and …, 2023 - Elsevier
Metallic nanoparticles are promising agents for increasing the effectiveness of radiation
therapy by making cells more sensitive to radiation. High atomic number nanoparticles …

Monte Carlo methods for medical imaging research

H Lee - Biomedical Engineering Letters, 2024 - Springer
In radiation-based medical imaging research, computational modeling methods are used to
design and validate imaging systems and post-processing algorithms. Monte Carlo methods …

A radiomic‐ and dosiomic‐based machine learning regression model for pretreatment planning in 177Lu‐DOTATATE therapy

D Plachouris, V Eleftheriadis, T Nanos… - Medical …, 2023 - Wiley Online Library
Background Standardized patient‐specific pretreatment dosimetry planning is mandatory in
the modern era of nuclear molecular radiotherapy, which may eventually lead to …

Optimization of Y-90 radioembolization imaging for Post-treatment Dosimetry on a long Axial Field-of-view PET/CT scanner

PM Linder, W Lan, NF Trautwein, J Brosch-Lenz… - Diagnostics, 2023 - mdpi.com
Background: PET imaging after yttrium-90 (Y-90) radioembolization is challenging because
of the low positron fraction of Y-90 (32× 10− 6). The resulting low number of events can be …

Optical Photon Propagation Characteristics and Thickness Optimization of LaCl3:Ce and LaBr3:Ce Crystal Scintillators for Nuclear Medicine Imaging

S Tseremoglou, C Michail, I Valais, K Ninos, A Bakas… - Crystals, 2023 - mdpi.com
The present study focuses on the determination of the optimal crystal thickness of LaCl3: Ce
and LaBr3: Ce crystal scintillators for Nuclear Medicine Imaging applications. A theoretical …

PET digitization chain for Monte Carlo simulation in GATE

J Salvadori, A Merlet, B Presles, J Cabello… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. We introduce a versatile methodology for the accurate modelling of PET imaging
systems via Monte Carlo simulations, using the Geant4 application for tomographic emission …

An international study of factors affecting variability of dosimetry calculations, part 3: contribution from calculating absorbed dose from time-integrated activity

J Brosch-Lenz, S Kurkowska, E Frey… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
Image-based dosimetry-guided radiopharmaceutical therapy has the potential to
personalize treatment by limiting toxicity to organs at risk and maximizing the therapeutic …

Annihilation photon GAN source model for PET Monte Carlo simulation

D Sarrut, A Etxebeste, T Kaprelian… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Following previous works on virtual sources model with Generative Adversarial
Network (GAN), we extend the proof of concept for generating back-to-back pairs of gammas …

A framework for prediction of personalized pediatric nuclear medical dosimetry based on machine learning and Monte Carlo techniques

V Eleftheriadis, G Savvidis, V Paneta… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective: A methodology is introduced for the development of an internal dosimetry
prediction toolkit for nuclear medical pediatric applications. The proposed study exploits …

[HTML][HTML] Theranostics and artificial intelligence: new frontiers in personalized medicine

GB Bilgin, C Bilgin, BJ Burkett, JJ Orme, DS Childs… - Theranostics, 2024 - ncbi.nlm.nih.gov
The field of theranostics is rapidly advancing, driven by the goals of enhancing patient care.
Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications …