Until the 196Os, complexation of alkali and alkaline earth metal cations was problematic.
Although such Ca2+ binders as ethylenediaminetetraacetic acid, EDTA, were well known …

Dehydroalanine is a synthetic precursor to a wide array of protein modifications. We
describe multiple methods for the chemical conversion of cysteine to dehydroalanine on …

Bonding of the neutral oxygen donor to metal ions is discussed in relation to metal ion
selectivity. Important factors are (a) inductive effects of alkyl groups attached to the oxygen …

A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields
by the room temperature reaction of amino acids with methanol in the presence of …

Abstract A series of N1, N3-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16
were prepared and their structures were confirmed by different spectral tools. The cytotoxic …

The discovery of efficient organocatalysts is generally carried out by thorough experimental
screening of different candidates. We recently reported an efficient organocatalyst for …

A mild and efficient procedure is described for the removal of the tert-butoxycarbonyl (BOC)
group using boron trifluoride etherate and molecular sieves in dichloromethane at room …

A novel and efficient method for the modification of amino acids using a dimethyl carbonate
(DMC) and acid system has been developed. N-Methylation, N, O-dimethylation, and N …

Based on the natural product terpestacin, seventeen derivatives (1–17) with various l-amino
acid side chains were designed and synthesized. Their anticancer activities against U87MG …

Recent advances in macrocyclic chemistry and its applications to supramolecular chemistry
are described. We first present concept and examples of “armed crown ethers”, which are …