Background: Green tea has been shown to have beneficial effects against a variety of
diseases such as cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative …

Although colorectal cancer (CRC) screening has reduced the incidence of and mortality from
CRC, chemoprevention strategies have the potential to further reduce CRC incidence and …

A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Background Patients with familial adenomatous polyposis have a nearly 100 percent risk of
colorectal cancer. In this disease, the chemopreventive effects of nonsteroidal …

Abstract Background/Aims: Several clinical, epidemiological, and animal studies indicate
that nonsteroidal anti-inflammatory drugs (NSAIDs) may alter the incidence of colorectal …

Numerous experimental, epidemiologic, and clinical studies suggest that nonsteroidal anti-
inflammatory drugs (NSAIDs), particularly the highly selective cyclooxygenase (COX)-2 …

Two cyclooxygenase isozymes catalyze conversion of arachidonic acid to prostaglandin H
2: constitutive COX-1 and inducible COX-2. To assess the role of COX-2 in colorectal …

Prostaglandin endoperoxide synthase 2, also referred to as cyclooxygenase 2 (COX-2), is a
key enzyme in the conversion of arachidonic acid to prostaglandins and other eicosanoids …

Evidence clearly shows a chemopreventive effect for aspirin and other non-steroidal anti-
inflammatory drugs (NSAIDs) on colorectal cancer and probably other cancer types; …

Background Randomised trials have shown that aspirin reduces the short-term risk of
recurrent colorectal adenomas in patients with a history of adenomas or cancer, but large …