Nuclear factor-κB (NF-κB) consists of a family of transcription factors that play critical roles in
inflammation, immunity, cell proliferation, differentiation, and survival. Inducible NF-κB …

Most chronic diseases, caused by lifestyle factors, appear to be linked to inflammation.
Inflammation is activated mechanistically, and nuclear factor-κB (NF-κB) is a significant …

A reciprocal regulation exists between the central nervous and immune systems through
which the CNS signals the immune system via hormonal and neuronal pathways and the …

Abstract Intercellular adhesion molecule‐1 (ICAM‐1, CD54) is an inducible cell adhesion
glycoprotein of the immunoglobulin supergene family expressed on the surface of a wide …

Reactive oxygen species (ROS), generated either extracellularly or intracellularly through
ligand-receptor interactions, can function as signal transduction molecules to activate the …

c-Rel is a member of the nuclear factor κB (NF-κB) transcription factor family. Unlike other NF-
κB proteins that are expressed in a variety of cell types, high levels of c-Rel expression are …

Glycosaminoglycans (GAG) are a group of negatively charged molecules that have been
shown to bind and directly regulate the bioactivity of growth factors and cytokines such as …

The mode of action of intranasal corticosteroids (INCS) is complex. It is not known whether
INCS penetrate the nasal mucosa or act on target cells; however, their low systemic activity …

It is well established that the NF-κB family of transcription factors serves a major role in
controlling gene expression in response to T cell activation, but the genome-wide roles of …

ICAM-1 is an Ig-like cell adhesion molecule expressed by several cell types, including the
endothelium. Cross-linking of ICAM-1 on the surface of different cell types has previously …