Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …

V Katju, U Bergthorsson - Genome Biology and Evolution, 2019 - academic.oup.com
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

Fitness effects of mutations in bacteria

I Gordo, L Perfeito, A Sousa - Journal of molecular microbiology and …, 2012 - karger.com
Mutation is the primary source of variation in any organism. Without it, natural selection
cannot operate and organisms cannot adapt to novel environments. Mutation is also …

Evaluating thermal performance of closely related taxa: Support for hotter is not better, but for unexpected reasons

DJS Montagnes, Q Wang, Z Lyu… - Ecological …, 2022 - Wiley Online Library
Temperature drives performance and therefore adaptation; to interpret and understand
these, thermal performance curves (TPC) are used, often through meta‐analyses, revealing …

Evolution of density‐dependent movement during experimental range expansions

EA Fronhofer, S Gut, F Altermatt - Journal of Evolutionary …, 2017 - academic.oup.com
Range expansions and biological invasions are prime examples of transient processes that
are likely impacted by rapid evolutionary changes. As a spatial process, range expansions …

Implications of clonality for ageing research

R Salguero-Gómez - Evolutionary Ecology, 2018 - Springer
Senescence, an organismal performance decline with age, has historically been considered
a universal phenomenon by evolutionary biologists and zoologist. Yet, increasing fertility …

Gene swamping alters evolution during range expansions in the protist Tetrahymena thermophila

F Moerman, EA Fronhofer, A Wagner… - Biology …, 2020 - royalsocietypublishing.org
At species' range edges, individuals often face novel environmental conditions that may limit
range expansion until populations adapt. The potential to adapt depends on genetic …

The distribution of mutational fitness effects of phage φX174 on different hosts

PF Vale, M Choisy, R Froissart, R Sanjuán… - Evolution, 2012 - academic.oup.com
Adaptation depends greatly on the distribution of mutation fitness effects (DMFE), but the
phenotypic expression of mutations is often environment dependent. The environments …

Evolution under pH stress and high population densities leads to increased density-dependent fitness in the protist Tetrahymena thermophila

F Moerman, A Arquint, S Merkli, A Wagner… - …, 2020 - academic.oup.com
Abiotic stress is a major force of selection that organisms are constantly facing. While the
evolutionary effects of various stressors have been broadly studied, it is only more recently …

The Rate and Effects of Spontaneous Mutation on Fitness Traits in the Social Amoeba, Dictyostelium discoideum

DW Hall, S Fox, JJ Kuzdzal-Fick… - G3: Genes …, 2013 - academic.oup.com
We performed a mutation accumulation (MA) experiment in the social amoeba Dictyostelium
discoideum to estimate the rate and distribution of effects of spontaneous mutations affecting …

Experimental Evolution in Tetrahymena

K Plum, J Tarkington, RA Zufall - Microorganisms, 2022 - mdpi.com
Experimental evolution has provided novel insight into a wide array of biological processes.
Species in the genus Tetrahymena are proving to be a highly useful system for studying a …