Human antimicrobial peptides and proteins

G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …

A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …

Antimicrobial coating of spider silk to prevent bacterial attachment on silk surgical sutures

AR Franco, EM Fernandes, MT Rodrigues… - Acta biomaterialia, 2019 - Elsevier
Microbial infections from post-surgery or other medical-related procedure is a serious health
problem. Nowadays, the research is focused on the development of new drug-free materials …

Review of antimicrobial peptides with anti‐Helicobacter pylori activity

A Neshani, H Zare, MR Akbari Eidgahi… - …, 2019 - Wiley Online Library
Background The emergence of antibiotic‐resistant Helicobacter pylori strains in recent years
has increased the need for finding an alternative in the post‐antibiotic era. One of the fields …

Nanomaterials-based combinatorial therapy as a strategy to combat antibiotic resistance

A León-Buitimea, CR Garza-Cárdenas… - Antibiotics, 2022 - mdpi.com
Since the discovery of antibiotics, humanity has been able to cope with the battle against
bacterial infections. However, the inappropriate use of antibiotics, the lack of innovation in …

Human antimicrobial peptides in ocular surface defense

I Mohammed, DG Said, HS Dua - Progress in retinal and eye research, 2017 - Elsevier
Sight depends on the passage of light through the transparent cornea and being focused on
the fovea. Its exposed position renders it vulnerable to microbial infection. The cornea has …

An aptamer-based sandwich assay for detection of alpha-defensin human neutrophil protein 1 on a microfluidic platform

R Gandotra, TW Chen, FC Kuo, MS Lee… - Biosensors and …, 2023 - Elsevier
The diagnosis of periprosthetic joint infection (PJI) remains a labor-intensive and
challenging issue, with life-threatening complications associated with misdiagnoses …

A paper-based aptamer-sandwich assay for detection of HNP 1 as a biomarker for periprosthetic joint infections on an integrated microfluidic platform

R Gandotra, FC Kuo, MS Lee, GB Lee - Analytica Chimica Acta, 2023 - Elsevier
Background Total joint arthroplasty (TJA) has significantly improved the quality of life for
millions suffering from end-stage arthritis. However, periprosthetic joint infections (PJI) …

Modulation of cathelicidin and defensins by histone deacetylase inhibitors: A potential treatment for multi-drug resistant infectious diseases

A Rodríguez-Carlos, YM Jacobo-Delgado… - Peptides, 2021 - Elsevier
Infectious diseases are an important growing public health problem, which perspective has
worsened due to the increasing number of drug-resistant strains in the last few years …

Antimicrobial peptides as antimicrobials for wound care management: a comprehensive review

KA Kanaujia, N Mishra, PS Rajinikanth… - Journal of Drug Delivery …, 2024 - Elsevier
Antimicrobial peptides (AMPs) are low-molecular-weight proteins having a presence in
almost all organisms, from prokaryotes to eukaryotes, and have been a fundamental part of …