The cognitive map in humans: spatial navigation and beyond

RA Epstein, EZ Patai, JB Julian, HJ Spiers - Nature neuroscience, 2017 - nature.com
The'cognitive map'hypothesis proposes that brain builds a unified representation of the
spatial environment to support memory and guide future action. Forty years of …

Functional organization of the hippocampal longitudinal axis

BA Strange, MP Witter, ES Lein, EI Moser - Nature reviews …, 2014 - nature.com
The precise functional role of the hippocampus remains a topic of much debate. The
dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and …

The role of the hippocampus in navigation is memory

H Eichenbaum - Journal of neurophysiology, 2017 - journals.physiology.org
There is considerable research on the neurobiological mechanisms within the hippocampal
system that support spatial navigation. In this article I review the literature on navigational …

The hippocampus in aging and disease: from plasticity to vulnerability

T Bartsch, P Wulff - Neuroscience, 2015 - Elsevier
The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …

A new neural framework for visuospatial processing

DJ Kravitz, KS Saleem, CI Baker… - Nature Reviews …, 2011 - nature.com
The division of cortical visual processing into distinct dorsal and ventral streams is a key
framework that has guided visual neuroscience. The characterization of the ventral stream …

A pathophysiological framework of hippocampal dysfunction in ageing and disease

SA Small, SA Schobel, RB Buxton, MP Witter… - Nature Reviews …, 2011 - nature.com
The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

Memory enhancement and deep-brain stimulation of the entorhinal area

N Suthana, Z Haneef, J Stern, R Mukamel… - … England Journal of …, 2012 - Mass Medical Soc
Background The medial temporal structures, including the hippocampus and the entorhinal
cortex, are critical for the ability to transform daily experience into lasting memories. We …

Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline

K Chang, JP Ling, J Redding-Ochoa, Y An, L Li… - Acta …, 2024 - Springer
LATE-NC, the neuropathologic changes of limbic-predominant age-related TAR DNA-
binding protein 43 kDa (TDP-43) encephalopathy are frequently associated with Alzheimer's …

Hippocampal vascular reserve associated with cognitive performance and hippocampal volume

V Perosa, A Priester, G Ziegler, A Cardenas-Blanco… - Brain, 2020 - academic.oup.com
Medial temporal lobe dependent cognitive functions are highly vulnerable to hypoxia in the
hippocampal region, yet little is known about the relationship between the richness of …

Navigating social space

M Schafer, D Schiller - Neuron, 2018 - cell.com
Cognitive maps are encoded in the hippocampal formation and related regions and range
from the spatial to the purely conceptual. Neural mechanisms that encode information into …