Analysis of matrix metalloproteinases, especially MMP‐8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases

T Sorsa, UK Gursoy, S Nwhator… - Periodontology …, 2016 - Wiley Online Library
Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

Realizing the clinical utility of saliva for monitoring oral diseases

JL Ebersole, H Hasturk, M Huber… - Periodontology …, 2024 - Wiley Online Library
In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …

The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions

L Tjäderhane, H Larjava, T Sorsa… - Journal of dental …, 1998 - journals.sagepub.com
Matrix metalloproteinases (MMPs) are a family of enzymes which, in concert, are capable of
degrading collagen. We investigated whether human MMPs could participate in the …

Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation

T Sorsa, L Tjäderhane, YT Konttinen, A Lauhio… - Annals of …, 2006 - Taylor & Francis
Matrix metalloproteinases (MMPs) form a family of enzymes that mediate multiple functions
both in the tissue destruction and immune responses related to periodontal inflammation …

Matrix metalloproteinases (MMPs) in oral diseases

T Sorsa, L Tjäderhane, T Salo - Oral diseases, 2004 - Wiley Online Library
Matrix metalloproteinases (MMPs) are a group of enzymes that in concert are responsible for
the degradation of most extracellular matrix proteins during organogenesis, growth and …

Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine

R Gendron, D Grenier, T Sorsa… - Clinical Diagnostic …, 1999 - Am Soc Microbiol
Matrix metalloproteinases (MMPs) are a host cell-derived proteolytic enzyme family which
plays a major role in tissue-destructive inflammatory diseases such as periodontitis. The aim …

Current developments in salivary diagnostics

CS Miller, JD Foley, AL Bailey, CL Campell… - Biomarkers in …, 2010 - Taylor & Francis
Salivary diagnostics is an emerging field that has progressed through several important
developments in the past decade, including the publication of the human salivary proteome …

Genetic susceptibility to periodontitis

ML Laine, W Crielaard, BG Loos - Periodontology 2000, 2012 - Wiley Online Library
In this systematic review, we explore and summarize the peer‐reviewed literature on
putative genetic risk factors for susceptibility to aggressive and chronic periodontitis. A …

The role of matrix metalloproteinases (MMPs) in human caries

C Chaussain-Miller, F Fioretti… - Journal of dental …, 2006 - journals.sagepub.com
The objective of this review is to summarize our understanding of the role of host matrix
metalloproteinases (MMPs) in the caries process and to discuss new therapeutic avenues …

Pulp inflammation diagnosis from clinical to inflammatory mediators: a systematic review

M Zanini, E Meyer, S Simon - Journal of endodontics, 2017 - Elsevier
Introduction Similar to other tissues, the dental pulp mounts an inflammatory reaction as a
way to eliminate pathogens and stimulate repair. Pulp inflammation is prerequisite for dentin …