Cerebellar hypoplasia (CH) refers to a cerebellum of reduced volume with preserved shape.
CH is associated with a broad heterogeneity in neuroradiologic features, etiologies, clinical …

The polycomb repressive complex 2 (PRC2) is responsible for catalyzing both di-and
trimethylation of histone H3 at lysine 27 (H3K27me2/3). The subunits of PRC2 are widely …

Human epidemiological studies have shown that paternal aging as one of the risk factors for
neurodevelopmental disorders, such as autism, in offspring. A recent study has suggested …

Epigenetic predisposition is thought to critically contribute to adult-onset disorders, such as
retinal neurodegeneration. The histone methyltransferase, enhancer of zeste homolog 2 …

The brain stem is composed of the midbrain (the mesencephalon) and the hindbrain (the
rhombencephalon), and is, at least during development, segmentally organized. The …

Many academic neurologists and neuropathologists who retire at the peak of their careers
continue to be productive in research and teaching, enhanced by years of experience and …

Due to advances in MR imaging and molecular genetics in recent years, there have been
attempts to classify malformations of the brain stem into distinct groups. In this review, we …

Prenatal disruptive injuries within one or both cerebellar hemispheres, which are mostly
caused by hemorrhages, are well known. Primary disruptive lesions of the brainstem …

The polycomb repressive complex 2 (PRC2) is responsible for catalyzing both di-and
trimethylation of histone H3 at lysine 27 (H3K27me2/3). The subunits of PRC2 are widely …