For the past 20 years, the recombination detection program (RDP) project has focused on
the development of a fast, flexible, and easy to use Windows-based recombination analysis …

Abstract The Stanford HIV Drug Resistance Database hosts a freely available online
genotypic resistance interpretation system called HIVdb to help clinicians and laboratories …

Genome Detective is an easy to use web-based software application that assembles the
genomes of viruses quickly and accurately. The application uses a novel alignment method …

Throughout the living world, genetic recombination and nucleotide substitution are the
primary processes that create the genetic variation upon which natural selection acts. Just …

Background Molecular techniques are established as routine in virological laboratories and
virus typing through (partial) sequence analysis is increasingly common. Quality assurance …

Viral sequence classification has wide applications in clinical, epidemiological, structural
and functional categorization studies. Most existing approaches rely on an initial alignment …

Background To investigate differences in pathogenesis, diagnosis and resistance pathways
between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed …

Interpreting the results of plasma human immunodeficiency virus type 1 (HIV-1) genotypic
drug-resistance tests is one of the most difficult tasks facing clinicians caring for HIV-1 …

Background The effect of transmitted drug resistance (TDR) on first-line combination
antiretroviral therapy (cART) for HIV-1 needs further study to inform choice of optimum drug …

Background Group A rotaviruses are the most common cause of severe diarrhea in infants
and children worldwide and continue to have a major global impact on childhood morbidity …