This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …

In less than five months, COVID-19 has spread from a small focus in Wuhan, China, to more
than 5 million people in almost every country in the world, dominating the concern of most …

In global terms, respiratory viral infection is a major cause of morbidity and mortality. Infancy,
in particular, is a time of increased disease susceptibility and severity. Early-life viral …

Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …

It has been suggested that some individuals may present genetic susceptibility to SARS‐
CoV‐2 infection, with particular research interest in variants of the ACE2 and TMPRSS2 …

The COVID-19 pandemic has strengthened the interest in the biological mechanisms
underlying the complex interplay between infectious agents and the human host. The …

The SARS-CoV-2 pandemic has become one of the most serious health concerns globally.
Although multiple vaccines have recently been approved for the prevention of coronavirus …

The SARS-CoV-2 pandemic raises many scientific and clinical questions. These include
how host genetic factors affect disease susceptibility and pathogenesis. New work is …

Objectives To assess associations between the functional polymorphisms G-2518A at the
chemokine (C–C motif) ligand 2 gene (CCL2) and mannose binding lectin (MBL) codon 54 …

Infection with respiratory viruses such as influenza, respiratory syncytial virus and
coronavirus provides a difficult immunological challenge for the host, where a balance must …