Advanced strategies for the regeneration of lumbar disc annulus fibrosus

J Tavakoli, AD Diwan, JL Tipper - International journal of molecular …, 2020 - mdpi.com
Damage to the annulus fibrosus (AF), the outer region of the intervertebral disc (IVD), results
in an undesirable condition that may accelerate IVD degeneration causing low back pain …

The role of microRNAs in 5‐FU resistance of colorectal cancer: Possible mechanisms

RM Marjaneh, M Khazaei, GA Ferns… - Journal of Cellular …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common cancers globally. Despite recent
advances in therapeutic approaches, this cancer continues to have a poor prognosis …

MiR-17 and miR-19 cooperatively promote skeletal muscle cell differentiation

D Kong, M He, L Yang, R Zhou, YQ Yan… - Cellular and Molecular …, 2019 - Springer
Skeletal myogenesis is a highly coordinated process that involves cell proliferation,
differentiation and fusion controlled by a complex gene regulatory network. The microRNA …

Phytosomal curcumin elicits anti-tumor properties through suppression of angiogenesis, cell proliferation and induction of oxidative stress in colorectal cancer

R Moradi-Marjaneh, SM Hassanian… - Current …, 2018 - ingentaconnect.com
Background: Colorectal cancer (CRC) is one of the most common causes of cancer-
associated mortality in the world. Anti-tumor effect of curcumin has been shown in different …

[HTML][HTML] Bioinformatics-based interaction analysis of miR-92a-3p and key genes in tamoxifen-resistant breast cancer cells

J Cun, Q Yang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
The abnormal expression of miR-92a-3p was detected in multiple cancers. However, the
biological role and underlying mechanism of miR-92a-3p in tamoxifen-resistant cells are still …

MicroRNAs as potential therapeutic targets to predict responses to oxaliplatin in colorectal cancer: From basic evidence to therapeutic implication

R Moradi Marjaneh, M Khazaei, GA Ferns, A Avan… - IUBMB …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common malignancies with poor prognosis.
Oxaliplatin‐based chemotherapy is an important treatment for CRC; however, the cells …

The importance of miRNAs and epigenetics in acute lymphoblastic leukemia prognosis

R Ranjbar, A Karimian, A Aghaie Fard… - Journal of cellular …, 2019 - Wiley Online Library
Acute lymphoblastic leukemia (ALL), one of the most common malignant human disorders,
originates in different important genetic lesions in T‐cell or B‐cell progenitors. ALL is a …

Understanding the CREB1-miRNA feedback loop in human malignancies

YW Wang, X Chen, R Ma, P Gao - Tumor Biology, 2016 - Springer
Abstract cAMP response element binding protein 1 (CREB1, CREB) is a key transcription
factor that mediates transcriptional responses to a variety of growth factors and stress …

Differential sensitivity of target genes to translational repression by miR-17~ 92

HY Jin, H Oda, P Chen, C Yang, X Zhou, SG Kang… - PLoS …, 2017 - journals.plos.org
MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of
hundreds of target genes and each to a small degree, but it remains unclear how small …

[HTML][HTML] The malignancy of miR-18a in human glioblastoma via directly targeting CBX7

W Wu, X Zhou, T Yu, Z Bao, T Zhi, K Jiang… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Aberrant levels of microRNAs (miRNAs) are linked to tumorigenesis and tumor progression.
Here we analyzed the expression of microRNA 18a in glioblastoma multiforme (GBM) within …