Using genetics for social science

KP Harden, PD Koellinger - Nature Human Behaviour, 2020 - nature.com
Social science genetics is concerned with understanding whether, how and why genetic
differences between human beings are linked to differences in behaviours and …

[HTML][HTML] Addictive and other mental disorders: a call for a standardized definition of dual disorders

N Szerman, M Torrens, R Maldonado… - Translational …, 2022 - nature.com
The persistent difficulty in conceptualizing the relationship between addictive and other
mental disorders stands out among the many challenges faced by the field of Psychiatry …

Polygenic scores in developmental psychology: Invite genetics in, leave biodeterminism behind

L Raffington, T Mallard… - Annual Review of …, 2020 - annualreviews.org
Polygenic scores offer developmental psychologists new methods for integrating genetic
information into research on how people change and develop across the life span. Indeed …

Examining the shared etiology of psychopathology with genome-wide association studies

TT Mallard, AD Grotzinger… - Physiological …, 2023 - journals.physiology.org
Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …

Genetics and child development: Recent advances and their implications for developmental research

E ArmstrongCarter, J Wertz… - Child Development …, 2021 - Wiley Online Library
Recent genetic discoveries offer a new lens through which to study cognitive, emotional,
behavioral, and social processes that are foundational to children's development. In this …

[HTML][HTML] Partial agonists and dual disorders: focus on dual schizophrenia

L Peris, N Szerman - Frontiers in Psychiatry, 2021 - frontiersin.org
Dual disorder is a term applied to patients with an addictive disorder and other mental
disorder. Epidemiological studies have established that dual disorders are an expectation …

Not just one p: Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

TT Mallard, RK Linnér, A Okbay, AD Grotzinger… - BioRxiv, 2019 - biorxiv.org
A single dimension of general psychopathology, p, has been hypothesized to represent a
general liability that spans multiple types of psychiatric disorders and non-clinical variation …

Selective allosteric modulation of muscarinic acetylcholine receptors for the treatment of schizophrenia and substance use disorders

LB Teal, RW Gould, AS Felts, CK Jones - Advances in Pharmacology, 2019 - Elsevier
Muscarinic acetylcholine receptor (mAChRs) subtypes represent exciting new targets for the
treatment of schizophrenia and substance use disorder (SUD). Recent advances in the …

Association between polygenic liability for schizophrenia and substance involvement: A nationwide populationbased study in Taiwan

SH Wang, RY Lai, YC Lee, MH Su… - Genes, Brain and …, 2020 - Wiley Online Library
Schizophrenia and substance involvement frequently cooccur in individuals, and a
bidirectional relationship between the two has been proposed; shared underlying genetic …

[HTML][HTML] Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an …

JJ Martínez-Magaña, AD Genis-Mendoza… - Brazilian Journal of …, 2021 - SciELO Brasil
Objective: Individuals with schizophrenia and substance use disorders have a poor
prognosis and increased psychiatric symptoms. The present study aimed to explore the …