Importance Appropriate use of antibiotics is life-saving in neonatal early-onset sepsis (EOS),
but overuse of antibiotics is associated with antimicrobial resistance and long-term adverse …

Background: Sepsis is a major cause of death in neonates. Knowledge about epidemiology,
risk factors, causative pathogens and outcome of neonatal sepsis is important to improve …

The term neonatal sepsis is used to describe a generalized bloodstream infection of
bacterial, viral, or fungal origin which is associated with hemodynamic changes and other …

Sepsis remains a leading cause of neonatal mortality, particularly in low-and lower-middle-
income countries (LLMIC). In the context of rising antimicrobial resistance, the etiology of …

Background: The epidemiology of early-onset sepsis (EOS) in China is poorly understood
because of the paucity of high-quality data. We aimed to examine the epidemiology …

Background Most studies regarding late-onset sepsis (LOS) address selected populations
(ie, neonates with low birth weight or extremely preterm neonates). Studying all age groups …

Background: Culture-negative late-onset sepsis (LOS) is commonly diagnosed in neonatal
intensive care units, while the outcomes of neonatal culture-negative LOS are not reported …

METHODS: In the 60-bed level IV NICU of an academic referral center, we used a quality
improvement framework to develop key drivers and interventions including (1) physician …

Objectives: Summarize the common etiologies of neonatal meningitis. Implement current
recommendations, including lumbar puncture, for evaluating patients with neonatal …

Abstract Background In 2013 German infection surveillance guidelines recommended
weekly colonization screening for multidrug-resistant (MDRO) or highly epidemic organisms …