Strategies for the nuclear delivery of metal complexes to cancer cells

M Huynh, R Vinck, B Gibert, G Gasser - Advanced Materials, 2024 - Wiley Online Library
The nucleus is an essential organelle for the function of cells. It holds most of the genetic
material and plays a crucial role in the regulation of cell growth and proliferation. Since …

Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients

JZ Wang, AP Landry, DR Raleigh, F Sahm… - Neuro …, 2024 - academic.oup.com
Meningiomas are the most common primary intracranial tumors in adults and are increasing
in incidence due to the aging population and increased access to neuroimaging. While most …

Urease-powered nanobots for radionuclide bladder cancer therapy

C Simó, M Serra-Casablancas, AC Hortelao… - Nature …, 2024 - nature.com
Bladder cancer treatment via intravesical drug administration achieves reasonable survival
rates but suffers from low therapeutic efficacy. To address the latter, self-propelled …

Recent Advances in 64Cu/67Cu-Based Radiopharmaceuticals

OO Krasnovskaya, D Abramchuck, A Erofeev… - International Journal of …, 2023 - mdpi.com
Copper-64 (T1/2= 12.7 h) is a positron and beta-emitting isotope, with decay characteristics
suitable for both positron emission tomography (PET) imaging and radiotherapy of cancer …

Radiotheranostics global market and future developments

A Al-Ibraheem, R Zimmermann, AS Abdlkadir… - Seminars in Nuclear …, 2024 - Elsevier
Radiotheranostics, a combination of diagnostic and therapeutic approaches, was first
utilized in cancer management using radiopharmaceuticals to both image and selectively …

Yolk-Shell Pst@ SiO2 decorated with functional guests: A new solid-phase extractant for highly effective separation of no carrier added 177Lu

X Fan, G Ma, H Peng, J Gao, Y Hu, B Li, J Liao… - Separation and …, 2025 - Elsevier
With the rapid development of 177 Lu-related radiopharmaceuticals, there is an urgent need
for large-scale production of 177 Lu efficiently. In this work, we employed yolk-shell Pst …

PET imaging of nectin-4: A promising tool for personalized/precision oncology

D Jiang, X Lan, W Cai - Clinical Cancer Research, 2023 - AACR
In a recent study, the authors developed a nectin-4–targeting bicyclic peptide–based
radiotracer, 68Ga-N188, for PET imaging of advanced urothelial cancer. Preclinical …

Prospects of nano-theranostic approaches against breast and cervical cancer

T Ria, R Roy, US Mandal, UH Sk - … et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
The bottleneck on therapeutics and diagnostics is removed by an alternate approach known
as theranostics which combines both therapeutics and diagnostics within a single platform …

[HTML][HTML] Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)

RP Baum, P Wang, V Jakobsson, T Zhao… - Theranostics, 2024 - ncbi.nlm.nih.gov
Rationale: Peptide receptor radionuclide therapy (PRRT) for the treatment of
neuroendocrine tumors (NETs) has been explored for more than two decades, but there are …

Recent Progress in the Development of Peptide-Drug Conjugates (PDCs) for Cancer Therapy

H He, X Deng, Z Wang, J Chen - European Journal of Medicinal Chemistry, 2024 - Elsevier
Peptide-drug conjugates (PDCs) are emerging therapeutic agents composed of peptides,
linkers, and payloads, which possess favorable targeting capability and can deliver enough …