New Halogenated Compounds from Halimeda macroloba Seaweed with Potential Inhibitory Activity against Malaria

AH Elmaidomy, EM Zahran, R Soltane, A Alasiri… - Molecules, 2022 - mdpi.com
Malaria is one of the most important infectious diseases worldwide. The causative of the
most severe forms of malaria, Plasmodium falciparum, has developed resistances against …

Evaluation of antiviral activity of Carica papaya leaves against SARS-CoV-2 assisted by metabolomic profiling

A Adel, MS Elnaggar, A Albohy, AA Elrashedy… - RSC …, 2022 - pubs.rsc.org
The COVID-19 pandemic caused a huge health crisis all over the globe. SARS-CoV-2 is the
virus responsible for the disease and it is highly contagious leaving millions of confirmed …

Aurasperone A inhibits SARS CoV-2 in vitro: an integrated in vitro and in silico study

MH ElNaggar, GM Abdelwahab, O Kutkat, M GabAllah… - Marine drugs, 2022 - mdpi.com
Several natural products recovered from a marine-derived Aspergillus niger were tested for
their inhibitory activity against SARS CoV-2 in vitro. Aurasperone A (3) was found to inhibit …

Wound healing potential of Cystoseira/mesenchymal stem cells in immunosuppressed rats supported by overwhelming immuno-inflammatory crosstalk

EM Zahran, RH Mohyeldin, FM Abd El-Mordy… - Plos one, 2024 - journals.plos.org
Wound healing, one of the most intricate and dynamic processes of the body, maintains skin
integrity following trauma. One of the main issues that still exists is impaired wound healing …

Wound Restorative Power of Halimeda macroloba/ Mesenchymal Stem Cells in Immunocompromised Rats via Downregulating Inflammatory/Immune Cross Talk

EM Zahran, RH Mohyeldin, FMA El-Mordy, SA Maher… - Marine Drugs, 2023 - mdpi.com
Impaired skin wound healing is still a major challenge, especially with immunocompromised
patients who express delayed healing and are susceptible to infections. Injection of rat …

Anti-otomycotic potential of nanoparticles of Moringa oleifera leaf extract: An integrated in vitro, in silico and phase 0 clinical study

EM Zahran, SA Mohamad, R Yahia, AM Badawi… - Food & Function, 2022 - pubs.rsc.org
Otomycosis is a serious superficial mycotic infection of the outer ear canal caused by some
pathogenic species of Candida and Aspergillus. The infection remains a challenge to …

Combination of Callyspongia sp. and Stem Cells for Wound Repair and Skin Regeneration: in Vivo and in Silico Evidences

E Maher Zahran, MF Abdelwahab… - Chemistry & …, 2024 - Wiley Online Library
Delayed healing of chronic wounds results in amputation and mortality rates in serious
cases. The present study examines the merged wound‐restorative efficacy of injectable …

Chemical Constituents and Anticancer Activities of Marine-Derived Fungus Trichoderma lixii

N Sirimangkalakitti, J Lin, K Harada, A Setiawan… - Molecules, 2024 - mdpi.com
The fungal genus Trichoderma is a rich source of structurally diverse secondary metabolites
with remarkable pharmaceutical properties. The chemical constituents and anticancer …

Antibiofilm potential of 6-methoxymellein from geranium-associated Aspergillus caespitosus endophyte against clinical isolates of dermatophytes: Phytochemical, in …

A Hagag, AM Abd El-Kader, MF Abdelwahab… - South African Journal of …, 2024 - Elsevier
Dermatophytes are saprophytic fungi which invade the skin and contribute to the
pathogenesis of Tinea corporis. Dermatophytes are resistant to conventional antifungal …