Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Internuclear distances represent one of the main structural constraints in molecular structure
determination using solid-state NMR spectroscopy, complementing chemical shifts and …

Progress in NMR in general and in biomolecular applications in particular is driven by
increasing magnetic-field strengths leading to improved resolution and sensitivity of the …

The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses
a severe threat to humanity and demands the redirection of scientific efforts and criteria to …

Cell-free protein synthesis (CFPS) systems are gaining more importance as universal tools
for basic research, applied sciences, and product development with new technologies …

Structural virology reveals the architecture underlying infection. While notably electron
microscopy images have provided an atomic view on viruses which profoundly changed our …

Solid-state NMR (ssNMR) is a versatile technique that can be used for the characterization
of various materials, ranging from small molecules to biological samples, including …

Magic angle spinning NMR rotating frame relaxation measurements provide a unique
experimental window into biomolecules dynamics, as is illustrated by numerous recent …

The Hepatitis C virus nonstructural protein 5A (NS5A) is a membrane‐associated protein
involved in multiple steps of the viral life cycle. Direct‐acting antivirals (DAAs) targeting …

ORF7b is an accessory protein of SARS-CoV-2, the virus behind the COVID-19 pandemic.
Using cell-free synthesized ORF7b, we experimentally show that ORF7b assembles into …