Gcoupler: An AI-enhanced tool unveiled Endogenous Intracellular Allosteric Modulators of Evolutionary Conserved GPCR-Gα Interface

SK Mohanty, A Mittal, A Gaur, Namra, S Duari… - bioRxiv, 2023 - biorxiv.org
Traditionally, the exogenous allosteric modulators of G protein-coupled receptors (GPCRs)
have been extensively investigated due to their pharmacological significance. However, to …

[PDF][PDF] Artificial Intelligence Uncovers Evolutionarily Conserved Intracellular Allosteric Modulators of GPCR-Gα Interface

S Mohanty, A Mittal, A Gaur, S Solanki, S Kumar… - 2023 - assets-eu.researchsquare.com
Traditionally, the exogenous allosteric modulators of G protein-coupled receptors (GPCRs)
have been extensively investigated due to their pharmacological signi cance. However, to …