Update on hepatitis E virology: Implications for clinical practice

Y Debing, D Moradpour, J Neyts, J Gouttenoire - Journal of hepatology, 2016 - Elsevier
Hepatitis E virus (HEV) is a positive-strand RNA virus transmitted by the fecal-oral route. The
7.2 kb genome encodes three open reading frames (ORF) which are translated into (i) the …

Clinical manifestations, pathogenesis and treatment of hepatitis E virus infections

S Lhomme, O Marion, F Abravanel, J Izopet… - Journal of clinical …, 2020 - mdpi.com
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis throughout the
world. Most infections are acute but they can become chronic in immunocompromised …

Distinct entry mechanisms for nonenveloped and quasi-enveloped hepatitis E viruses

X Yin, C Ambardekar, Y Lu, Z Feng - Journal of virology, 2016 - Am Soc Microbiol
The hepatitis E virus (HEV) sheds into feces as nonenveloped virions but circulates in the
blood in a membrane-associated, quasi-enveloped form (eHEV). Since the eHEV virions …

Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers

SM Robinson, G Tsueng, J Sin, V Mangale… - PLoS …, 2014 - journals.plos.org
Coxsackievirus B3 (CVB3), a member of the picornavirus family and enterovirus genus,
causes viral myocarditis, aseptic meningitis, and pancreatitis in humans. We genetically …

EASL Clinical Practice Guidelines on hepatitis E virus infection

HR Dalton, N Kamar, SA Baylis, D Moradpour… - Journal of …, 2018 - Elsevier
Infection with hepatitis E virus (HEV) is a significant cause of morbidity and mortality,
representing an important global health problem. Our understanding of HEV has changed …

[HTML][HTML] Viruses and the autophagy pathway

WT Jackson - Virology, 2015 - Elsevier
Studies of the cellular autophagy pathway have exploded over the past twenty years. Now
appreciated as a constitutive degradative mechanism that promotes cellular homeostasis …

Hepatitis A: epidemiology in resource-poor countries

R Aggarwal, A Goel - Current opinion in infectious diseases, 2015 - journals.lww.com
Resource-poor countries should closely monitor the epidemiology of HAV infection and
periodically undertake cost-effectiveness analyses of HAV immunization strategies. This …

Characterization of the lipid envelope of exosome encapsulated HEV particles protected from the immune response

S Chapuy-Regaud, M Dubois, C Plisson-Chastang… - Biochimie, 2017 - Elsevier
The hepatitis E virus (HEV) is the most common cause of acute hepatitis worldwide.
Although HEV is a small, naked RNA virus, HEV particles become associated with lipids in …

Hepatitis E pathogenesis

S Lhomme, O Marion, F Abravanel, S Chapuy-Regaud… - Viruses, 2016 - mdpi.com
Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe,
causing fulminant hepatitis and extra-hepatic manifestations, including neurological and …

Virus–host cell interplay during hepatitis E virus infection

MH Wißing, Y Brüggemann, E Steinmann, D Todt - Trends in microbiology, 2021 - cell.com
The molecular interplay between cellular host factors and viral proteins is a continuous
process throughout the viral life cycle determining virus host range and pathogenesis. The …