Azole-resistant aspergillosis: epidemiology, molecular mechanisms, and treatment

A Chowdhary, C Sharma, JF Meis - The Journal of infectious …, 2017 - academic.oup.com
Aspergillus fumigatus remains the most common species in all pulmonary syndromes,
followed by Aspergillus flavus which is a common cause of allergic rhinosinusitis …

[HTML][HTML] Triazole resistance in Aspergillus fumigatus: recent insights and challenges for patient management

PPA Lestrade, JF Meis, WJG Melchers… - Clinical Microbiology and …, 2019 - Elsevier
Abstract Background Triazole resistance in Aspergillus fumigatus is widespread and
threatens first-line triazole therapy in patients with Aspergillus diseases. Objectives To give …

Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus

E Snelders, SMT Camps, A Karawajczyk… - PloS one, 2012 - journals.plos.org
Background Azoles play an important role in the management of Aspergillus diseases.
Azole resistance is an emerging global problem in Aspergillus fumigatus, and may develop …

Aspergillosis due to Voriconazole Highly Resistant Aspergillus fumigatus and Recovery of Genetically Related Resistant Isolates From Domiciles

JWM van der Linden, SMT Camps… - Clinical infectious …, 2013 - academic.oup.com
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and
complicates the management of patients with Aspergillus-related diseases. Selection of …

Azole resistance mechanisms in Aspergillus: update and recent advances

A Pérez-Cantero, L López-Fernández, J Guarro… - International journal of …, 2020 - Elsevier
Aspergillus fumigatus is the main causal agent of invasive aspergillosis (IA), however other
species of the genus can also cause IA, such as Aspergillus flavus, Aspergillus terreus …

Echinocandin and triazole antifungal susceptibility profiles for clinical opportunistic yeast and mold isolates collected from 2010 to 2011: application of new CLSI …

MA Pfaller, SA Messer, LN Woosley… - Journal of clinical …, 2013 - Am Soc Microbiol
ABSTRACT The SENTRY Antimicrobial Surveillance Program monitors global susceptibility
and resistance rates of newer and established antifungal agents. We report the …

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Update on antifungal resistance in Aspergillus and Candida

MC Arendrup - Clinical microbiology and infection, 2014 - Wiley Online Library
Antifungal resistance in C andida and A spergillus may be either intrinsic or acquired and
may be encountered in the antifungal drug exposed but also the antifungal drug‐naïve …

Aspergillus fumigatus and aspergillosis: From basics to clinics

A Arastehfar, A Carvalho, J Houbraken… - Studies in …, 2021 - ingentaconnect.com
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Azole resistance in Aspergillus fumigatus: a growing public health concern

E Vermeulen, K Lagrou, PE Verweij - Current opinion in infectious …, 2013 - journals.lww.com
Triazoles are the mainstay of therapy in infections with the opportunistic fungus Aspergillus
fumigatus. The emergence of resistance is, therefore, of clinical concern. The first reports of …