In silico methods for predicting functional synonymous variants

BC Lin, U Katneni, KI Jankowska, D Meyer… - Genome Biology, 2023 - Springer
Single nucleotide variants (SNVs) contribute to human genomic diversity. Synonymous
SNVs are previously considered to be “silent,” but mounting evidence has revealed that …

miR-1207-5p Can Contribute to Dysregulation of Inflammatory Response in COVID-19 via Targeting SARS-CoV-2 RNA

G Bertolazzi, C Cipollina, PV Benos… - Frontiers in Cellular …, 2020 - frontiersin.org
The present study focuses on the role of human miRNAs in SARS-CoV-2 infection. An
extensive analysis of human miRNA binding sites on the viral genome led to the …

Analysis of the p53/microRNA network in cancer

M Kaller, S Hünten, H Siemens… - Systems Biology of …, 2022 - Springer
MicroRNAs (miRNAs) are important components of the signaling cascades that mediate and
regulate tumor suppression exerted by p53. This review illustrates some of the main …

[HTML][HTML] Circular RNA_0006014 promotes breast cancer progression through sponging miR-885-3p to regulate NTRK2 and PIK3/AKT pathway

X Zhou, W Jian, Q Luo, W Zheng, X Deng… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Breast cancer is the most common cancer in women worldwide. Numerous reports have
demonstrated that circRNAs play an essential role in regulating the biological characteristics …

A microRNA that controls the emergence of embryonic movement

JAC Menzies, AM Chagas, T Baden, CR Alonso - Elife, 2024 - elifesciences.org
Movement is a key feature of animal systems, yet its embryonic origins are not fully
understood. Here, we investigate the genetic basis underlying the embryonic onset of …

[HTML][HTML] Acupuncture therapy protects PCOS patients with diabetes by regulating miR-32-3p/PLA2G4A pathway

J Wu, X Chen - American Journal of Translational Research, 2021 - ncbi.nlm.nih.gov
Objective: To investigate the potential miRNA-mRNA network co-expressed in polycystic
ovary syndrome (PCOS) and diabetes, and explore the molecular mechanism of traditional …

Non-Canonical Targets of MicroRNAs: Role in Transcriptional Regulation, Disease Pathogenesis and Potential for Therapeutic Targets

A Ray, A Sarkar, S Banerjee, K Biswas - MicroRNA, 2024 - benthamdirect.com
MicroRNAs are a class of regulatory, non-coding small ribonucleic acid (RNA) molecules
found in eukaryotes. Dysregulated expression of microRNAs can lead to downregulation or …

Impact of MICA 3′ UTR allelic variability on miRNA binding prediction, a bioinformatic approach

K Toledo-Stuardo, CH Ribeiro, I Campos, S Tello… - Frontiers in …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs that participate as powerful genetic
regulators. MiRNAs can interfere with cellular processes by interacting with a broad …

Resources and Methods for the Analysis of MicroRNA Function in Drosophila

S Mukherjee, N Sokol - Drosophila: Methods and Protocols, 2022 - Springer
Since the widespread discovery of microRNAs (miRNAs) 20 years ago, the Drosophila
melanogaster model system has made important contributions to understanding the biology …

MBS: a genome browser annotation track for high-confident microRNA binding sites in whole human transcriptome

W Arancio, N Sciaraffa, C Coronnello - Database, 2023 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) that play a role in
many regulatory pathways in eukaryotes. They usually exert their functions by binding …