Background: The comparative effectiveness of localized prostate cancer treatments is
largely unknown. Purpose: To compare the effectiveness and harms of treatments for …

CONTEXT: Androgen deprivation therapy (ADT) for prostate cancer (PCa) represents one of
the most effective systemic palliative treatments known for solid tumors. Although clinical …

PURPOSE: To provide updated American Brachytherapy Society (ABS) guidelines for
transrectal ultrasound-guided transperineal interstitial permanent prostate brachytherapy …

In December 1995, the AUA published the Report on the Management of Clinically
Localized Prostate Cancer. 1 The document was the culmination of six years of work by 17 …

Purpose We evaluated whether the timing of fatal myocardial infarction (MI) was influenced
by the administration of androgen suppression therapy (AST). Patients and Methods The …

Background Hormone therapy for early prostate cancer has demonstrated an improvement
in clinical and pathological variables, but not always an improvement in overall survival. We …

Background Androgen deprivation is an established treatment regimen for disseminated
prostate cancer; however, its role in patients with localised cancer is less clear. We did a …

BACKGROUND: We performed a systematic review and meta-analysis of randomised trials
of neo-adjuvant hormone therapy (NHT) in localised and locally advanced prostate cancer …

Increasing numbers of men with non-metastatic disease are receiving androgen deprivation
therapy (ADT) for a variety of indications, some of which are supported by evidence from …

PURPOSE The sequencing of androgen-deprivation therapy (ADT) with radiotherapy (RT)
may affect outcomes for prostate cancer in an RT-field size-dependent manner. Herein, we …