The prevalence and incidence of cancers has risen over the last decade. Available
treatments have improved outcomes, yet mortality and morbidity remain high, creating an …

During the early development of Placentalia, a distinctive projection emerges at the posterior
embryonic–extraembryonic interface of the conceptus; its fingerlike shape presages …

Zika virus (ZIKV) infection can lead to neurological complications and fetal defects, and it
has attracted global public health concerns. Effective treatment for ZIKV infection remains …

In most multicellular organisms, including mammals, germ cells are at the origin of new
organisms and ensure the continuation of the genetic and epigenetic information across the …

STUDY QUESTION Which set of antibodies can be used to identify migratory and early post-
migratory human primordial germ cells (hPGCs)? STUDY FINDING We validated the …

STUDY DESIGN, SIZE, DURATION: This immunofluorescence study investigated the
expression of putative hPGC markers in the caudal part of a single human embryo at 4.5 …

Purpose. Interferon‐induced transmembrane protein 3 (IFITM3) is a key signaling molecule
regulating cell growth in some tumors, but its function and mechanism in hepatocellular …

Hypoblast/visceral endoderm assists in amniote nutrition, axial positioning and formation of
the gut. Here, we provide evidence, currently limited to humans and non-human primates …

The H9N2 avian influenza virus is a pandemic threat which has repeatedly caused infection
in humans and shows enhanced replication and transmission in mice. Previous reports …

The ovary functions to chaperone the most precious cargo for female individuals, the oocyte,
thereby allowing the passage of genetic material to subsequent generations. Within the …