Gene regulatory networks and signaling pathways in palatogenesis and cleft palate: a comprehensive review
HJ Won, JW Kim, HS Won, JO Shin - Cells, 2023 - mdpi.com
Palatogenesis is a complex and intricate process involving the formation of the palate
through various morphogenetic events highly dependent on the surrounding context. These …
through various morphogenetic events highly dependent on the surrounding context. These …
Molecular and cellular mechanisms of palate development
C Li, Y Lan, R Jiang - Journal of dental research, 2017 - journals.sagepub.com
Development of the mammalian secondary palate involves highly dynamic morphogenetic
processes, including outgrowth of palatal shelves from the oral side of the embryonic …
processes, including outgrowth of palatal shelves from the oral side of the embryonic …
Lhx6 deficiency causes human embryonic palatal mesenchymal cell mitophagy dysfunction in cleft palate
H Luo, HC Ieong, R Li, D Huang, D Chen, X Chen… - Molecular …, 2024 - Springer
Overconsumption of retinoic acid (RA) or its analogues/derivatives has been linked to
severe craniomaxillofacial malformations, such as cleft palate and midface hypoplasia. It has …
severe craniomaxillofacial malformations, such as cleft palate and midface hypoplasia. It has …
The bone-forming properties of periosteum-derived cells differ between harvest sites
The development of alternatives for autologous bone grafts is a major focus of bone tissue
engineering. To produce living bone-forming implants, skeletal stem and progenitor cells …
engineering. To produce living bone-forming implants, skeletal stem and progenitor cells …
Alx1 Deficient Mice Recapitulate Craniofacial Phenotype and Reveal Developmental Basis of ALX1-Related Frontonasal Dysplasia
Loss of ALX1 function causes the frontonasal dysplasia syndrome FND3, characterized by
severe facial clefting and microphthalmia. Whereas the laboratory mouse has been the …
severe facial clefting and microphthalmia. Whereas the laboratory mouse has been the …
[HTML][HTML] Single-cell transcriptomic resolution of osteogenesis during craniofacial morphogenesis
Craniofacial morphogenesis depends on complex cell fate decisions during the
differentiation of post-migratory cranial neural crest cells. Molecular mechanisms of cell …
differentiation of post-migratory cranial neural crest cells. Molecular mechanisms of cell …
Down-regulation of miR-214 reverses erlotinib resistance in non-small-cell lung cancer through up-regulating LHX6 expression
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are standard
treatments for advanced non-small-cell lung cancer (NSCLC) patients. However, acquired …
treatments for advanced non-small-cell lung cancer (NSCLC) patients. However, acquired …
Association of low‐frequency genetic variants in regulatory regions with nonsyndromic orofacial clefts
Genome‐wide scans have shown that common risk alleles for orofacial clefts (OFC) tend to
be located in noncoding regulatory elements and cumulatively explain only part of the …
be located in noncoding regulatory elements and cumulatively explain only part of the …
Expression of forkhead box transcription factor genes Foxp1 and Foxp2 during jaw development
JM Cesario, AA Almaidhan, J Jeong - Gene Expression Patterns, 2016 - Elsevier
Abstract Development of the face is regulated by a large number of genes that are
expressed in temporally and spatially specific patterns. While significant progress has been …
expressed in temporally and spatially specific patterns. While significant progress has been …
Lhx6 regulates canonical Wnt signaling to control the fate of mesenchymal progenitor cells during mouse molar root patterning
Mammalian tooth crown formation has long served as a model for investigating how
patterning and morphogenesis are orchestrated during development. However, the …
patterning and morphogenesis are orchestrated during development. However, the …