Global hydrocephalus epidemiology and incidence: systematic review and meta-analysis

MC Dewan, A Rattani, R Mekary, LJ Glancz… - Journal of …, 2018 - thejns.org
OBJECTIVE Hydrocephalus is one of the most common brain disorders, yet a reliable
assessment of the global burden of disease is lacking. The authors sought a reliable …

Hydrocephalus in children

KT Kahle, AV Kulkarni, DD Limbrick, BC Warf - The lancet, 2016 - thelancet.com
Hydrocephalus is a common disorder of cerebral spinal fluid (CSF) physiology resulting in
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …

The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus

SM Robert, BC Reeves, E Kiziltug, PQ Duy, JK Karimy… - Cell, 2023 - cell.com
The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks …

Hydrocephalus: historical analysis and considerations for treatment

A Hochstetler, J Raskin, BL Blazer-Yost - European journal of medical …, 2022 - Springer
Hydrocephalus is a serious condition that affects patients of all ages, resulting from a
multitude of causes. While the etiologies of hydrocephalus are numerous, many of the acute …

Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence

SB Hladky, MA Barrand - Fluids and Barriers of the CNS, 2014 - Springer
Interstitial fluid (ISF) surrounds the parenchymal cells of the brain and spinal cord while
cerebrospinal fluid (CSF) fills the larger spaces within and around the CNS. Regulation of …

Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus

C Sadegh, H Xu, J Sutin, B Fatou, S Gupta, A Pragana… - Neuron, 2023 - cell.com
Post-hemorrhagic hydrocephalus (PHH) refers to a life-threatening accumulation of
cerebrospinal fluid (CSF) that occurs following intraventricular hemorrhage (IVH). An …

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

JK Karimy, BC Reeves, E Damisah, PQ Duy… - Nature Reviews …, 2020 - nature.com
Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

[HTML][HTML] Endoscopic treatment versus shunting for infant hydrocephalus in Uganda

AV Kulkarni, SJ Schiff… - … England Journal of …, 2017 - Mass Medical Soc
Background Postinfectious hydrocephalus in infants is a major health problem in sub-
Saharan Africa. The conventional treatment is ventriculoperitoneal shunting, but surgeons …

Combined endoscopic third ventriculostomy and choroid plexus cauterization as primary treatment for infant hydrocephalus: a prospective North American series

SSD Stone, BC Warf - Journal of Neurosurgery: Pediatrics, 2014 - thejns.org
Object Combined endoscopic third ventriculostomy with choroid plexus cauterization
(ETV/CPC) enhances the likelihood of shunt freedom over ETV alone, and thus avoidance of …

Tracking calcium dynamics and immune surveillance at the choroid plexus blood-cerebrospinal fluid interface

FB Shipley, N Dani, H Xu, C Deister, J Cui, JP Head… - Neuron, 2020 - cell.com
The choroid plexus (ChP) epithelium is a source of secreted signaling factors in
cerebrospinal fluid (CSF) and a key barrier between blood and brain. Here, we develop …