The principle of vinylogy states that the electronic effects of a functional group in a molecule
are possibly transmitted to a distal position through interposed conjugated multiple bonds …

Chiral spiropyrazolones are unique frameworks widely found in a large family of medicinally
relevant compounds with various biological activities. Substantial research efforts have been …

As a powerful synthon, pyrazolone has widely been exploited for the construction of various
chiral pyrazoles/pyrazolones which hold great potential in the development of …

Developing diversity-oriented synthetic approaches for medium-sized rings is of great
interest, and the divergent synthesis of medium-sized rings with different ring sizes poses a …

Asymmetric reactions merging organocatalysis and metal catalysis significantly broaden the
scope of organic synthesis. Nevertheless, the accomplishment of stereoselective …

A catalytic asymmetric [3+ 2] cyclization of novel 4-isothiocyanato pyrazolones and isatin-
derived ketimines was developed, delivering a wide range of intriguing dispirotriheterocyclic …

Organocatalytic asymmetric [3+ 3] annulations of isatin-derived MBH carbonates and indolin-
2-imines were efficiently achieved. This appears to be the first enantioselective approach for …

A palladium-catalyzed enantioselective [4+ 2] cycloaddition reaction of vinyl
benzoxazinones with sulfamate-derived cyclic imines is described, affording the …

A novel Lewis base-catalyzed [4+ 3] annulation process for the construction of benzo [b]
oxepine scaffolds has been developed. 1, 4-Diazabicyclo [2.2. 2] octane (DABCO) promotes …

The phosphine-catalyzed tandem annulation of allenylic alcohols with 1, 1-dicyanoalkenes
has been developed, giving various bicyclic tetrahydrocyclopentafuran derivatives in 40 …