Indian medicinal plants as a source of antimycobacterial agents
It is estimated that one-third of the world's population is infected with tubercle bacillus and
the problem of tuberculosis (TB) has been intensified due to HIV pandemic providing a large …
the problem of tuberculosis (TB) has been intensified due to HIV pandemic providing a large …
Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised, non …
RL Goodall, SK Meredith, AJ Nunn, A Bayissa… - The Lancet, 2022 - thelancet.com
Background The STREAM stage 1 trial showed that a 9-month regimen for the treatment of
rifampicin-resistant tuberculosis was non-inferior to the 20-month 2011 WHO-recommended …
rifampicin-resistant tuberculosis was non-inferior to the 20-month 2011 WHO-recommended …
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics
This article describes plug-based microfluidic technology that enables rapid detection and
drug susceptibility screening of bacteria in samples, including complex biological matrices …
drug susceptibility screening of bacteria in samples, including complex biological matrices …
Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis
R Rustomjee, AH Diacon, J Allen… - Antimicrobial agents …, 2008 - Am Soc Microbiol
ABSTRACT Tibotec Medicinal Compound 207 (TMC207) is a novel diarylquinoline with a
unique mode of action that targets mycobacterial ATP synthase. TMC207 exhibits high in …
unique mode of action that targets mycobacterial ATP synthase. TMC207 exhibits high in …
New quinoline derivatives: Synthesis and investigation of antibacterial and antituberculosis properties
S Eswaran, AV Adhikari, IH Chowdhury, NK Pal… - European journal of …, 2010 - Elsevier
Four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl
aniline through multi-step reactions. In the reaction sequence, substituted aniline was …
aniline through multi-step reactions. In the reaction sequence, substituted aniline was …
Resazurin reduction assays for screening of anti-tubercular compounds against dormant and actively growing Mycobacterium tuberculosis, Mycobacterium bovis BCG …
Objectives To develop simple, rapid, low-cost and robust assays for screening drugs against
dormant and actively growing mycobacteria. Methods Actively growing aerobic and hypoxia …
dormant and actively growing mycobacteria. Methods Actively growing aerobic and hypoxia …
Green synthesis of colloidal selenium nanoparticles in starch solutions and investigation of their photocatalytic, antimicrobial, and cytotoxicity effects
In this research, we have offered a green and new synthesizing procedure for selenium
nanoparticles (Se-NPs) through the utilization of Na 2 SeO 3, in which starch has a role of …
nanoparticles (Se-NPs) through the utilization of Na 2 SeO 3, in which starch has a role of …
[HTML][HTML] Rapid diagnosis of drug-resistant tuberculosis–opportunities and challenges
Global tuberculosis (TB) eradication is undermined by increasing prevalence of emerging
resistance to available drugs, fuelling ongoing demand for more complex diagnostic and …
resistance to available drugs, fuelling ongoing demand for more complex diagnostic and …
Bedaquiline Drug Resistance Emergence Assessment in Multidrug-Resistant Tuberculosis (MDR-TB): a 5-Year Prospective In Vitro Surveillance Study of Bedaquiline …
K Kaniga, R Hasan, R Jou… - Journal of Clinical …, 2022 - Am Soc Microbiol
ABSTRACT Bedaquiline Drug Resistance Emergence Assessment in Multidrug-resistant
tuberculosis (MDR-TB)(DREAM) was a 5-year (2015 to 2019) phenotypic drug resistance …
tuberculosis (MDR-TB)(DREAM) was a 5-year (2015 to 2019) phenotypic drug resistance …
Comparative evaluation of the nitrate reduction assay, the MTT test, and the resazurin microtitre assay for drug susceptibility testing of clinical isolates of …
E Montoro, D Lemus, M Echemendia… - Journal of …, 2005 - academic.oup.com
Objectives: To evaluate the performance of three rapid low-cost methods for the detection of
resistance to first-line drugs in Mycobacterium tuberculosis. Methods: One hundred M …
resistance to first-line drugs in Mycobacterium tuberculosis. Methods: One hundred M …