In ischemic stroke, the primary neuronal injury caused by the disruption of energy supply is
further exacerbated by secondary sterile inflammation. The inflammatory cascade is largely …

Traditionally, in vitro flow chamber experiments and in vivo arterial thrombosis studies have
been proved to be of vital importance to elucidate the mechanisms of platelet thrombus …

The involvement of purinergic signalling in the physiology of erythrocytes, platelets and
leukocytes was recognised early. The release of ATP and the expression of purinoceptors …

Determination of the patient-specific response to antiplatelet agents facilitates proper dosing
for both acute and chronic prophylaxis.“Closed” systems (with or without flow) may fail to …

Cell–fluid and cell–cell interactions are critical components of many physiological and
pathological conditions in the microvasculature. Similarly, particle–cell interactions play an …

Objectives Angiographic high thrombus burden (HTB) is associated with increased adverse
cardiovascular events in patients with ST-elevation myocardial infarction (STEMI). HbA1c …

Advances in microfabrication techniques have enabled the production of inexpensive and
reproducible microfluidic systems for conducting biological and biochemical experiments at …

This is the first report on the characterization of a snaclec (RVsnaclec) purified from Daboia
russelii russelii venom. The RVsnaclec is a heterodimer of two subunits, α (15.1 kDa) and β …

C‐peptide is a cleavage product of proinsulin that acts on different type of cells, such as
blood and endothelial cells. C‐peptide biological effects may be different in type 1 and type …

BACKGROUND: It has been well documented that ATP activates NOS enzymes and causes
increased NO production in several cell types. Although RBC known to possesses eNOS …