Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Chiral pharmaceuticals: A review on their environmental occurrence and fate processes

E Sanganyado, Z Lu, Q Fu, D Schlenk, J Gan - Water Research, 2017 - Elsevier
More than 50% of pharmaceuticals in current use are chiral compounds. Enantiomers of the
same pharmaceutical have identical physicochemical properties, but may exhibit differences …

Chiral recognition in separation science–an update

GKE Scriba - Journal of Chromatography a, 2016 - Elsevier
Stereospecific recognition of chiral molecules is an important issue in various aspects of life
sciences and chemistry including analytical separation sciences. The basis of analytical …

Chiral stationary phases for liquid chromatography: recent developments

J Teixeira, ME Tiritan, MMM Pinto, C Fernandes - Molecules, 2019 - mdpi.com
The planning and development of new chiral stationary phases (CSPs) for liquid
chromatography (LC) are considered as continuous and evolutionary issues since the …

From natural products to new synthetic small molecules: A journey through the world of xanthones

MMM Pinto, A Palmeira, C Fernandes, DISP Resende… - Molecules, 2021 - mdpi.com
This work reviews the contributions of the corresponding author (MMMP) and her research
group to Medicinal Chemistry concerning the isolation from plant and marine sources of …

Synthetic cathinones: recent developments, enantioselectivity studies and enantioseparation methods

AS Almeida, B Silva, PG Pinho, F Remião… - Molecules, 2022 - mdpi.com
New psychoactive substances represent a public health threat since they are not controlled
by international conventions, are easily accessible online and are sold as a legal alternative …

Analysis, fate and toxicity of chiral non-steroidal anti-inflammatory drugs in wastewaters and the environment: a review

B Petrie, D Camacho-Muñoz - Environmental chemistry letters, 2021 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are found in the aquatic environment
globally. Such drugs including naproxen, ibuprofen and ketoprofen are chiral molecules …

Enantioseparation of chiral pharmaceuticals in biomedical and environmental analyses by liquid chromatography: An overview

AR Ribeiro, AS Maia, QB Cass, ME Tiritan - Journal of Chromatography B, 2014 - Elsevier
This review aims to present the issues associated to enantioseparation of chiral
pharmaceuticals in biological and environmental matrices using chiral stationary phases …

Chiral recognition in separation sciences. Part II: Macrocyclic glycopeptide, donor-acceptor, ion-exchange, ligand-exchange and micellar selectors

GKE Scriba - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
The understanding of the molecular basis of the stereoselective formation of diastereomeric
guest-host complexes for the rationalization of the enantioseparation process in …

Chiral drug analysis in forensic chemistry: an overview

C Ribeiro, C Santos, V Gonçalves, A Ramos, C Afonso… - Molecules, 2018 - mdpi.com
Many substances of forensic interest are chiral and available either as racemates or pure
enantiomers. Application of chiral analysis in biological samples can be useful for the …