Role of the CCL2‐CCR2 signalling axis in cancer: mechanisms and therapeutic targeting

M Xu, Y Wang, R Xia, Y Wei, X Wei - Cell proliferation, 2021 - Wiley Online Library
The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and
progression of various cancers. CCL2 can activate tumour cell growth and proliferation …

Recent advances in cell penetrating peptide-based anticancer therapies

J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Tumor microenvironment components: Allies of cancer progression

PIR Franco, AP Rodrigues, LB de Menezes… - … -Research and Practice, 2020 - Elsevier
Cancer is a disease that affects millions of individuals worldwide and has a great impact on
public health. Therefore, the study of tumor biology and an understanding of how the …

The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis

T Yoshimura, C Li, Y Wang, A Matsukawa - Cellular & Molecular …, 2023 - nature.com
Breast cancer is the most prevalent cancer worldwide, and metastasis is the leading cause
of death in cancer patients. Human monocyte chemoattractant protein-1 (MCP-1/CCL2) was …

Prognostic significance of immune landscape in tumour microenvironment of endometrial cancer

BL Li, XP Wan - Journal of Cellular and Molecular Medicine, 2020 - Wiley Online Library
Tumour microenvironment (TME) is crucial to tumorigenesis. This study aimed to uncover
the differences in immune phenotypes of TME in endometrial cancer (EC) using Uterine …

TIGIT blockade exerts synergistic effects on microwave ablation against cancer

Y Chen, H Huang, Y Li, W Xiao, Y Liu, R Chen… - Frontiers in …, 2022 - frontiersin.org
Background Combination immunotherapy based on immune checkpoint inhibitors (ICIs) has
shown great success in the treatment of many types of cancers and has become the …

[HTML][HTML] Circ_0039569 promotes renal cell carcinoma growth and metastasis by regulating miR-34a-5p/CCL22

C Jin, L Shi, Z Li, W Liu, B Zhao, Y Qiu… - American journal of …, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) belong to non-coding RNAs and are known as key regulators in
gene regulation. CircRNAs involve in the various biological processes of cancer. However …

Interleukin‐33‐nuclear factor‐κB‐CCL2 signaling pathway promotes progression of esophageal squamous cell carcinoma by directing regulatory T cells

Y Yue, J Lian, T Wang, C Luo, Y Yuan, G Qin… - Cancer …, 2020 - Wiley Online Library
Esophageal cancer is currently one of the most fatal cancers. However, there is no effective
treatment. Increasing evidence suggests that interleukin (IL)‐33 has a significant role in …

3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy

M Sharifi, Q Bai, MMN Babadaei, F Chowdhury… - Journal of Controlled …, 2021 - Elsevier
The bioprinting technique with specialized tissue production allows the study of biological,
physiological, and behavioral changes of cancerous and non-cancerous tissues in response …

Migratory engineering of T cells for cancer therapy

S Michaelides, H Obeck, D Kechur, S Endres, S Kobold - Vaccines, 2022 - mdpi.com
Adoptive cell therapy (ACT) and chimeric antigen receptor (CAR) T cell therapy in particular
represents an adaptive, yet versatile strategy for cancer treatment. Convincing results in the …