Bacterial infections represent a significant health threat globally, and are responsible for the
majority of hospital-acquired infections, leading to extensive mortality and burden on global …

Quinoline and quinolone motifs which act as structural subunits of more complex natural
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …

Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent
bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid …

The structural features of copper (II), nickel (II), cobalt (II) and zinc (II) complexes with the
antimicrobial drugs quinolones and non-steroidal anti-inflammatory drugs (NSAIDs) as …

Five novel metal complexes of the quinolone antibacterial agent ciprofloxacin with Mn2+,
Fe3+, Co2+, Ni2+ and MoO22+ have been prepared and characterized with …

In the era of escalating antimicrobial resistance, the need for antibacterial drugs with novel
or improved modes of action (MOAs) is a health concern of utmost importance. Adding or …

Zinc complexes with the third-generation quinolone antibacterial drugs levofloxacin and
sparfloxacin have been synthesized and characterized. The deprotonated quinolones act as …

We have synthesized and characterized a novel copper (II) complex of the fluoroquinolone
antibacterial drug N-propyl-norfloxacin (Hpr-norf) in the presence of 1, 10-phenanthroline …

Molecular docking was used to predict the binding between moxifloxacin (H 2 L) and the
receptors of breast cancer mutant (3hb5), prostate cancer mutant (2q7k), crystal structure E …

The neutral mononuclear copper complex with the quinolone antibacterial drug N-propyl-
protected norfloxacin, Hpr-norfloxacin, in the presence of the nitrogen donor heterocyclic …