[HTML][HTML] Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review

AR Gomes, CL Varela, AS Pires… - Bioorganic …, 2023 - Elsevier
Guanidines are fascinating small nitrogen-rich organic compounds, which have been
frequently associated with a wide range of biological activities. This is mainly due to their …

Cystic fibrosis, CFTR, and colorectal cancer

P Scott, K Anderson, M Singhania… - International journal of …, 2020 - mdpi.com
Cystic fibrosis (CF), caused by biallelic inactivating mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) gene, has recently been categorized as a …

Identifying gut microbiota associated with colorectal cancer using a zero-inflated lognormal model

D Ai, H Pan, X Li, Y Gao, G Liu, LC Xia - Frontiers in microbiology, 2019 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer worldwide. Its incidence is still
increasing, and the mortality rate is high. New therapeutic and prognostic strategies are …

Lysates of Lactobacillus acidophilus combined with CTLA-4-blocking antibodies enhance antitumor immunity in a mouse colon cancer model

Q Zhuo, B Yu, J Zhou, J Zhang, R Zhang, J Xie… - Scientific reports, 2019 - nature.com
Previous reports have suggested that many gut microbiomes were associated with the
development of colorectal cancer (CRC), and could modulate response to numerous forms …

[HTML][HTML] The role of microbiota in gastrointestinal cancer and cancer treatment: chance or curse?

A Smet, J Kupcinskas, A Link, GL Hold… - Cellular and Molecular …, 2022 - Elsevier
The gastrointestinal (GI) tract is home to a complex and dynamic community of
microorganisms, comprising bacteria, archaea, viruses, yeast, and fungi. It is widely …

Role of gut microbiota and probiotics in colorectal cancer: onset and progression

E Torres-Maravilla, AS Boucard, AH Mohseni… - Microorganisms, 2021 - mdpi.com
The gut microbiota plays an important role in maintaining homeostasis in the human body,
and the disruption of these communities can lead to compromised host health and the onset …

Navigating beyond associations: Opportunities to establish causal relationships between the gut microbiome and colorectal carcinogenesis

FS Baas, N Brusselaers, ID Nagtegaal, L Engstrand… - Cell Host & Microbe, 2024 - cell.com
The gut microbiota has been recognized as an important determinant in the initiation and
progression of colorectal cancer (CRC), with recent studies shining light on the molecular …

The human microbiome in relation to cancer risk: a systematic review of epidemiologic studies

I Huybrechts, S Zouiouich, A Loobuyck… - … Biomarkers & Prevention, 2020 - AACR
The microbiome has been hypothesized to play a role in cancer development. Because of
the diversity of published data, an overview of available epidemiologic evidence linking the …

Alterations in the gut microbiome and suppression of histone deacetylases by resveratrol are associated with attenuation of colonic inflammation and protection …

HR Alrafas, PB Busbee, KN Chitrala… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is known to significantly increase the risk for development
of colorectal cancer (CRC), suggesting inflammation and cancer development are closely …

Gut microbiota manipulation as a tool for colorectal cancer management: recent advances in its use for therapeutic purposes

F Perillo, C Amoroso, F Strati, MR Giuffrè… - International Journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a multifaceted disease influenced by both environmental and
genetic factors. A large body of literature has demonstrated the role of gut microbes in …