ABSTRACT NK cell effector function is regulated by a range of activating and inhibitory
receptors, and many of their known ligands are MHC class I molecules. Human NK …

Endometriosis affects more than 10% of women, causing significant pain and morbidity. It is
also a significant cause of infertility. The aetiology of the disease remains an enigma, and …

Killer cell immunoglobulin‐like receptors (KIRs) have a central role in the control of natural
killer (NK) cell function. The functions of the activating KIRs, as compared to those of the …

HLA haplotype-homozygous (HLA-homo) induced pluripotent stem cells (iPSCs) are being
prepared to be used for allogeneic transplantation of regenerated tissue into recipients …

Background Kidney transplantation is a life-saving treatment for patients with end-stage
renal disease. However, despite progress in surgical techniques and patient management …

Endometriosis is a common gynecological disease defined by the presence of endometrial-
like tissue outside the uterus, most frequently on the pelvic viscera and ovaries, which is …

Endometriosis shares similarities with several autoimmune diseases. The human leukocyte
antigen (HLA)-C genotype is associated with several human autoimmune diseases. HLA-C …

Killer cell immunoglobulin-like receptors (KIRs) are a family of cell surface inhibitory or
activating receptors expressed on natural killer cells and some subpopulations of T …

Killer immunoglobulin‐like receptors (KIRs) play an essential role in the regulation of natural
killer (NK) activity, allowing NK cells to sense and respond to human leukocyte antigen …

Type 1 diabetes mellitus (T1D) is an autoimmune disease caused by the destruction of
insulin-producing β-cells in the pancreas by cytotoxic T-cells. To date, there are no drugs …