[HTML][HTML] ROS/oxidative stress signaling in osteoarthritis

P Lepetsos, AG Papavassiliou - … et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Osteoarthritis is the most common joint disorder with increasing prevalence due to aging of
the population. Its multi-factorial etiology includes oxidative stress and the overproduction of …

The role of cytokines in posttraumatic arthritis

SA Olson, P Horne, B Furman, J Huebner… - JAAOS-Journal of the …, 2014 - journals.lww.com
The development of arthritis after joint injury is commonly known as posttraumatic arthritis
(PTA). The inciting traumatic event may range from cartilage contusion and bone bruise …

Inducible nitric oxide synthase as a target for osteoarthritis treatment

A Leonidou, P Lepetsos, M Mintzas… - Expert Opinion on …, 2018 - Taylor & Francis
Introduction: Inducible nitric oxide synthase (iNOS) is the enzyme responsible for the
production of nitric oxide (NO), a major proinflammatory and destructive mediator in …

The effect of kaempferol and apigenin on allogenic synovial membrane-derived stem cells therapy in knee osteoarthritic male rats

F Estakhri, MR Panjehshahin, N Tanideh, R Gheisari… - The Knee, 2020 - Elsevier
Background Based on the anti-inflammatory and anti-oxidant properties of kaempferol and
apigenin, we hypothesized that co-injection of these phytochemicals would increase the …

Novel hyaluronic acid–methotrexate conjugates for osteoarthritis treatment

A Homma, H Sato, A Okamachi, T Emura… - Bioorganic & medicinal …, 2009 - Elsevier
Hyaluronic acid (HA) provides synovial fluid viscoelasticity and has a lubricating effect.
Injections of HA preparations into the knee joint are widely used as osteoarthritis therapy …

Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes

F Hu, D Zhu, W Pei, I Lee, X Zhang, L Pan… - International …, 2019 - Elsevier
Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disorder, which may lead
to joint disabilities. So far the pathogenesis of RA remains largely undetermined, and there …

[PDF][PDF] 大黄酸及其衍生物药理作用研究新进展

李晓红, 李蒙, 陶艳蓉 - 现代药物与临床, 2010 - tiprpress.com
大黄酸及其衍生物药理作用研究新进展 Page 1 现代药物与临床 Drugs & Clinic 2010 年第25 卷
第6 期 417 大黄酸及其衍生物药理作用研究新进展 李晓红1,李蒙1,陶艳蓉2* (1.中国医学科学院药 …

Development, optimisation, and evaluation of nanoencapsulated diacerein emulgel for potential use in osteoarthritis

B Siddiqui, AU Rehman, IU Haq… - Journal of …, 2020 - Taylor & Francis
Aim This study aimed to utilise the proficient function of diacerein (DCR) and anti-
inflammatory polymers to develop sustained release nanoencapsulated emulgel for …

Intra-articular transplantation of allogeneic BMMSCs rehabilitates cartilage injury of antigen-induced arthritis

H Liu, J Ding, C Wang, J Wang, Y Wang… - … Engineering Part A, 2015 - liebertpub.com
Apart from the immunosuppressive property, which has been widely investigated in the
treatment of various autoimmune diseases, bone marrow mesenchymal stem cells …

Comparison of volumetric bone mineral density in the operated and contralateral knee after anterior cruciate ligament and reconstruction: a 1‐year follow‐up study …

A Mündermann, N Payer, G Felmet… - Journal of Orthopaedic …, 2015 - Wiley Online Library
The purpose of this study was to quantify changes in volumetric bone mineral density
(vBMD) in the tibial plateau of the operated and contralateral leg measured using peripheral …