Cryoprotectant toxicity: facts, issues, and questions

BP Best - Rejuvenation research, 2015 - liebertpub.com
High levels of penetrating cryoprotectants (CPAs) can eliminate ice formation during
cryopreservation of cells, tissues, and organs to cryogenic temperatures. But CPAs become …

Freeze-drying of nanoparticles: How to overcome colloidal instability by formulation and process optimization

E Trenkenschuh, W Friess - European journal of pharmaceutics and …, 2021 - Elsevier
Lyophilization of nanoparticle (NP) suspensions is a promising technology to improve
stability, especially during long-term storage, and offers new routes of administration in solid …

The heat shock response: life on the verge of death

K Richter, M Haslbeck, J Buchner - Molecular cell, 2010 - cell.com
Organisms must survive a variety of stressful conditions, including sudden temperature
increases that damage important cellular structures and interfere with essential functions. In …

Recent developments in the field of bending rigidity measurements on membranes

R Dimova - Advances in colloid and interface science, 2014 - Elsevier
This review gives a brief overview of experimental approaches used to assess the bending
rigidity of membranes. Emphasis is placed on techniques based on the use of giant …

Metabolism of oligosaccharides and starch in lactobacilli: a review

MG Gänzle, R Follador - Frontiers in microbiology, 2012 - frontiersin.org
Oligosaccharides, compounds that are composed of 2–10 monosaccharide residues, are
major carbohydrate sources in habitats populated by lactobacilli. Moreover, oligosaccharide …

Effect of trehalose on protein structure

NK Jain, I Roy - Protein Science, 2009 - Wiley Online Library
Trehalose is a ubiquitous molecule that occurs in lower and higher life forms but not in
mammals. Till about 40 years ago, trehalose was visualized as a storage molecule, aiding …

Trehalose: current use and future applications

S Ohtake, YJ Wang - Journal of pharmaceutical sciences, 2011 - Elsevier
Trehalose, a disaccharide of glucose, has been reported to accumulate in many organisms
that can withstand extended periods of inanimation. Since this discovery, the properties of …

An overview of liposome lyophilization and its future potential

C Chen, D Han, C Cai, X Tang - Journal of controlled release, 2010 - Elsevier
Lyophilization is a promising approach to ensure the long-term stability of liposomes. After
decades of studies in this field, different lyoprotective mechanisms, such as water …

Preservation of micro-organisms by drying; a review

CA Morgan, N Herman, PA White, G Vesey - Journal of microbiological …, 2006 - Elsevier
The preservation of micro-organisms by different drying methodologies has been used for
decades. Freeze drying in particular is the preferred method for transporting and storing vast …

Drying techniques of probiotic bacteria as an important step towards the development of novel pharmabiotics

G Broeckx, D Vandenheuvel, IJJ Claes… - International journal of …, 2016 - Elsevier
The increasing knowledge about the human microbiome leads to the awareness of how
important probiotics can be for our health. Although further substantiation is required, it …