The brain is a remarkably complex organ responsible for a wide range of functions,
including the modulation of emotional states and movement. Neuronal circuits are believed …

Post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) are often comorbid.
Few treatments exist to reduce comorbid PTSD/AUD. Elucidating the mechanisms …

Alcohol use disorder (AUD) is a chronically relapsing disease characterized by loss of
control in seeking and consuming alcohol (ethanol) driven by the recruitment of brain stress …

Abstract Alcohol Use Disorder (AUD) is a prevalent and debilitating condition characterized
by an inability to control alcohol consumption despite adverse consequences. Current …

Hyperkateifia and stress-induced alcohol cravings drive relapse in individuals with alcohol
use disorder (AUD). The brain stress signal norepinephrine (also known as noradrenaline) …

Repetitive bouts of binge drinking can lead to neuroplastic events that alter ethanol's
pharmacologic effects and perpetuate excessive consumption. The corticotropin-releasing …

Alcohol use disorder (AUD) is a complex psychiatric disease characterized by periods of
heavy drinking and periods of withdrawal. Chronic exposure to ethanol causes profound …

Corticotropin-releasing factor (CRF, encoded by Crh) signaling is thought to play a critical
role in the development of excessive alcohol drinking and the emotional and physical pain …

Background Binge alcohol drinking is a dangerous behavior that can contribute to the
development of more severe alcohol use disorder. Importantly, the rate and severity of …

Alcohol use disorder (AUD) is a chronic alcohol-related disorder that typically presents as
uncontrolled drinking and preoccupation with alcohol. A key component of AUD research is …