Aging and atrial fibrillation: A vicious circle
P Gao, X Gao, B Xie, G Tse, T Liu - International Journal of Cardiology, 2024 - Elsevier
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia observed in clinical
practice. Its prevalence increases dramatically with advancing age. This review article …
practice. Its prevalence increases dramatically with advancing age. This review article …
Imbalance of ER and mitochondria interactions: prelude to cardiac ageing and disease?
J Li, D Zhang, BJJM Brundel, M Wiersma - Cells, 2019 - mdpi.com
Cardiac disease is still the leading cause of morbidity and mortality worldwide, despite some
exciting and innovative improvements in clinical management. In particular, atrial fibrillation …
exciting and innovative improvements in clinical management. In particular, atrial fibrillation …
Metformin attenuates ER stress–induced mitochondrial dysfunction
Endoplasmic reticulum (ER) stress, a disturbance of the ER function, contributes to cardiac
injury. ER and mitochondria are closely connected organelles within cells. ER stress …
injury. ER and mitochondria are closely connected organelles within cells. ER stress …
Hypothermic oxygenated perfusion attenuates DCD liver ischemia–reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum …
P Yue, X Lv, J You, Y Zou, J Luo, Z Lu, H Cao… - Cellular & Molecular …, 2023 - Springer
Background Hepatic ischemia–reperfusion injury (IRI) in donation after cardiac death (DCD)
donors is a major determinant of transplantation success. Endoplasmic reticulum (ER) stress …
donors is a major determinant of transplantation success. Endoplasmic reticulum (ER) stress …
Mitofusin 2 inhibits bladder cancer cell proliferation and invasion via the Wnt/β‑catenin pathway
G Pang, Q Xie, J Yao - Oncology letters, 2019 - spandidos-publications.com
The present study aimed to investigate the biological role of the mitochondrial GTPase
mitofusin‑2 (MFN2) in bladder cancer. MFN2 mRNA expression in tumor and paired …
mitofusin‑2 (MFN2) in bladder cancer. MFN2 mRNA expression in tumor and paired …
HAX1-Overexpression Augments Cardioprotective Efficacy of Stem Cell-Based Therapy Through Mediating Hippo-Yap Signaling
WF Cai, L Jiang, J Liang, S Dutta, W Huang… - Stem Cell Reviews and …, 2024 - Springer
Although stem/progenitor cell therapy shows potential for myocardial infarction repair,
enhancing the therapeutic efficacy could be achieved through additional genetic …
enhancing the therapeutic efficacy could be achieved through additional genetic …
N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) attenuates silicotic fibrosis by suppressing apoptosis of alveolar type II epithelial cells via mediation of endoplasmic …
L Zhang, D Xu, Q Li, Y Yang, H Xu, Z Wei… - Toxicology and applied …, 2018 - Elsevier
Damage to alveolar epithelial cells (AECs) caused by long-term inhalation of large amounts
of silica dust plays a significant role in the pathology of silicosis. The present study was …
of silica dust plays a significant role in the pathology of silicosis. The present study was …
Extracellular Vesicles Isolated from Equine Adipose-Derived Stromal Stem Cells (ASCs) Mitigate Tunicamycin-Induced ER Stress in Equine Corneal Stromal Stem …
JM Meissner, A Chmielińska, R Ofri… - Current issues in …, 2024 - mdpi.com
Corneal ulcers, characterized by severe inflammation of the cornea, can lead to serious,
debilitating complications and may be vision-threatening for horses. In this study, we aimed …
debilitating complications and may be vision-threatening for horses. In this study, we aimed …
Upregulation of let-7f-2-3p by long noncoding RNA NEAT1 inhibits XPO1-mediated HAX-1 nuclear export in both in vitro and in vivo rodent models of doxorubicin …
Y Liu, C Duan, W Liu, X Chen, Y Wang, X Liu, J Yue… - Archives of …, 2019 - Springer
Clinical application of doxorubicin (Dox) is limited due to its undesirable side effects,
especially cardiotoxicity. Several microRNAs (miRNAs) such as microRNA-140-5p and miR …
especially cardiotoxicity. Several microRNAs (miRNAs) such as microRNA-140-5p and miR …
The endoplasmic reticulum stress inducer thapsigargin enhances the toxicity of ZnO nanoparticles to macrophages and macrophage-endothelial co-culture
G Chen, Y Shen, X Li, Q Jiang, S Cheng, Y Gu… - Environmental …, 2017 - Elsevier
It was recently shown that exposure to ZnO nanoparticles (NPs) could induce endoplasmic
reticulum (ER) stress both in vivo and in vitro, but the role of ER stress in ZnO NP induced …
reticulum (ER) stress both in vivo and in vitro, but the role of ER stress in ZnO NP induced …