The Genes–Stemness–Secretome Interplay in Malignant Pleural Mesothelioma: Molecular Dynamics and Clinical Hints

GM Stella, C Marchiò, E Bari, I Ferrarotti… - International Journal of …, 2023 - mdpi.com
MPM has a uniquely poor somatic mutational landscape, mainly driven by environmental
selective pressure. This feature has dramatically limited the development of effective …

[HTML][HTML] ONCOS-102 plus pemetrexed and platinum chemotherapy in malignant pleural mesothelioma: a randomized phase 2 study investigating clinical outcomes …

S Ponce, S Cedrés, C Ricordel, N Isambert… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background ONCOS-102, an oncolytic adenovirus expressing granulocyte-macrophage
colony-stimulating factor, can alter the tumor microenvironment to an immunostimulatory …

Development in the Study of Natural Killer Cells for Malignant Peritoneal Mesothelioma Treatment

YT Liu, HL Wu, YD Su, Y Wang, Y Li - Cancer Biotherapy & …, 2024 - liebertpub.com
Malignant peritoneal mesothelioma (MPeM) is a rare primary malignant tumor originating
from peritoneal mesothelial cells. Insufficient specificity of the symptoms and their frequent …

TROP2 expression and SN38 antitumor activity in malignant pleural mesothelioma cells provide a rationale for antibody-drug conjugate therapy

L Hegedüs, Ö Okumus, F Mairinger, T Ploenes… - Lung Cancer, 2023 - Elsevier
Objectives Malignant pleural mesothelioma (MPM) is an aggressive cancer which at large is
not amenable to curative surgery. Despite the recent approval of immune checkpoint …

[HTML][HTML] Zimberelimab plus chemotherapy as the first-line treatment of malignant peritoneal mesothelioma: A case report and review of literature

XD Peng, ZY You, LX He, Q Deng - World Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Malignant peritoneal mesothelioma (MPeM) is a rare cancer with a poor
prognosis at advanced stage, and the standard first-line treatment for inoperable patients is …

[PDF][PDF] Patient with recurrent paratesticular malignant mesothelioma and multiple primary neoplasms

KH Kim, Y Lee, JY Ku, HK Ha, HJ Park - Journal of Men's Health, 2024 - oss.jomh.org
Paratesticular malignant mesothelioma (MM) is a rare tumor frequently associated with
asbestos exposure. Therefore, we present an even rarer case of a 78-year-old male patient …

Epithelioid pleural mesothelioma successfully treated with perioperative immunotherapy: a case report

G Yamazaki, A Fujiwara-Kuroda, J Muto, H Ujiie… - General Thoracic and …, 2024 - Springer
Background Pleural mesothelioma, characterized by a dismal prognosis even with
multimodal therapy, has seen emerging interest in immune checkpoint inhibitors (ICIs) due …

Caractérisation des facteurs de résistance des cancers thoraciques au virus oncolytique de la rougeole en modèle 3D

M Grard - 2023 - theses.hal.science
Notre équipe étudie l'utilisation de virus oncolytiques dans le mésothéliome pleural malin
(MPM). En particulier, nous étudions les mécanismes de sensibilité et de résistance des …

[PDF][PDF] RNA interference of the E3 ubiquitin ligase RAD18 promotes senescence and reduces tumor growth in pleural mesothelioma

H Brossel - 2023 - orbi.uliege.be
Pleural mesothelioma (MPM) is a rare and aggressive cancer of the pleura, mainly induced
by asbestos exposure. The standard chemotherapy of MPM consists in a combination of …

A Esternotomia mediana para remoção de mesotelioma pleural em mediastino de cão

CKN Calva, AV Hörbe, ESV de Aguiar… - Acta Scientiae …, 2023 - seer.ufrgs.br
Background: Malignant pleural mesothelioma (MPM) is a neoplasm with low incidence in
small animals, and the possible causes are poorly elucidated but may be related to contact …