Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

Type 1 diabetes mellitus is believed to result from destruction of the insulin-producing β-cells
in pancreatic islets that is mediated by autoimmune mechanisms. The classic view is that …

Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

Probiotics and prebiotics are microbiota-management tools for improving host health. They
target gastrointestinal effects via the gut, although direct application to other sites such as …

The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …

Conceptual scientific and medical advances have led to a recent realization that there may
be no single, one-size-fits-all diet and that differential human responses to dietary inputs …

Cereal grains are the main dietary source of energy, carbohydrates, and plant proteins world-
wide. Currently, only 41% of grains are used for human consumption, and up to 35% are …

The extreme diversity of the human immune system, forged and maintained throughout
evolutionary history, provides a potent defense against opportunistic pathogens. At the same …

The gut microbiota (GM) is defined as the community of microorganisms (bacteria, archaea,
fungi, viruses) colonizing the gastrointestinal tract. GM regulates various metabolic pathways …

Gut microbiota plays a fundamental role within human health, and exerts key functions
within the human body. Diet is one of the most powerful modulators of gut microbiota …